• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

沙特阿拉伯一家三级医院中新冠肺炎患者嗅觉功能障碍的发生率

Incidence of Olfactory Dysfunction in Patients with COVID-19 in a Tertiary Hospital in Saudi Arabia.

作者信息

Alfallaj Rayan, AlSkait Ghada, Alamari Nouf, Alfawzan Lama, Abualgasem Mohammed, Alotaibi Naif H, Sumaily Ibrahim, Alarifi Ibrahim, Alsaleh Saad

机构信息

Otolaryngology-Head & Neck Surgery Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Allergy Rhinol (Providence). 2022 Nov 25;13:21526575221140809. doi: 10.1177/21526575221140809. eCollection 2022 Jan-Dec.

DOI:10.1177/21526575221140809
PMID:36452479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9703475/
Abstract

BACKGROUND

Coronavirus disease (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2, a novel virus that emerged in China in December 2019. In many cases of COVID-19, olfactory dysfunction (OD) is the only symptom.

OBJECTIVES

This study aimed to examine the incidence of OD in patients with COVID-19 and identify an association between OD and COVID-19-related morbidity and admission.

DESIGN

This was a cross-sectional study.

METHODS

Real-time reverse transcription polymerase chain reaction-confirmed cases of COVID-19 from the Security Forces Hospital electronic registry from June 2020 to September 2020 were included in our study. Data on medical background, severity of the disease, and other related factors were collected through phone calls and electronic healthcare systems and analyzed to investigate OD in the participants.

RESULTS

Of the participants, 68% had OD, with a mean recovery time of 18 days and a mean follow-up time of 129 days (76-211 days). OD was negatively correlated with admission and morbidity.

CONCLUSION

OD is a common presentation of COVID-19 and is more prevalent in mild cases of infection.

摘要

背景

冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2引起,这是一种于2019年12月在中国出现的新型病毒。在许多COVID-19病例中,嗅觉功能障碍(OD)是唯一症状。

目的

本研究旨在调查COVID-19患者中OD的发生率,并确定OD与COVID-19相关发病率及入院情况之间的关联。

设计

这是一项横断面研究。

方法

我们的研究纳入了2020年6月至2020年9月安全部队医院电子登记册中经实时逆转录聚合酶链反应确诊的COVID-19病例。通过电话和电子医疗系统收集有关医疗背景、疾病严重程度及其他相关因素的数据,并进行分析以调查参与者的OD情况。

结果

参与者中,68%有OD,平均恢复时间为18天,平均随访时间为129天(76 - 211天)。OD与入院及发病率呈负相关。

结论

OD是COVID-19的常见表现,在轻度感染病例中更为普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/75d12ee70846/10.1177_21526575221140809-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/57b4114a3623/10.1177_21526575221140809-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/75d12ee70846/10.1177_21526575221140809-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/57b4114a3623/10.1177_21526575221140809-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/75d12ee70846/10.1177_21526575221140809-fig2.jpg

相似文献

1
Incidence of Olfactory Dysfunction in Patients with COVID-19 in a Tertiary Hospital in Saudi Arabia.沙特阿拉伯一家三级医院中新冠肺炎患者嗅觉功能障碍的发生率
Allergy Rhinol (Providence). 2022 Nov 25;13:21526575221140809. doi: 10.1177/21526575221140809. eCollection 2022 Jan-Dec.
2
Olfactory Dysfunction and Sinonasal Symptomatology in COVID-19: Prevalence, Severity, Timing, and Associated Characteristics.新冠病毒感染患者的嗅觉功能障碍和鼻-鼻窦症状:流行率、严重程度、出现时间和相关特征。
Otolaryngol Head Neck Surg. 2020 Jul;163(1):114-120. doi: 10.1177/0194599820929185. Epub 2020 May 19.
3
Long-standing gustatory and olfactory dysfunction in COVID-19 patients: a prospective study.新冠病毒患者长期存在的味觉和嗅觉功能障碍:一项前瞻性研究。
Eur Arch Otorhinolaryngol. 2022 Sep;279(9):4633-4640. doi: 10.1007/s00405-022-07428-1. Epub 2022 Jun 29.
4
Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 2019 patients with olfactory dysfunction.288 例新冠病毒病嗅觉障碍患者的临床系列中嗅觉恢复的预测因素。
Eur J Neurol. 2021 Nov;28(11):3702-3711. doi: 10.1111/ene.14994. Epub 2021 Jul 9.
5
Olfactory and Gustatory Dysfunction in COVID-19 Patients from Northern India: A Cross-Sectional Observational Study.印度北部新冠肺炎患者的嗅觉和味觉功能障碍:一项横断面观察研究。
Indian J Otolaryngol Head Neck Surg. 2021 Jun;73(2):218-225. doi: 10.1007/s12070-021-02391-5. Epub 2021 Feb 10.
6
Testing for anosmia and ageusia in patients presenting to the emergency department with suspected coronavirus disease 2019 in Saudi Arabia.在沙特阿拉伯,对疑似2019冠状病毒病而前往急诊科就诊的患者进行嗅觉丧失和味觉丧失检测。
J Int Med Res. 2022 May;50(5):3000605221096280. doi: 10.1177/03000605221096280.
7
Smell and taste alterations in COVID-19: a cross-sectional analysis of different cohorts.COVID-19 患者的嗅觉和味觉改变:不同队列的横断面分析。
Int Forum Allergy Rhinol. 2020 Aug;10(8):955-962. doi: 10.1002/alr.22610. Epub 2020 Jun 25.
8
Epidemiological, otolaryngological, olfactory and gustatory outcomes according to the severity of COVID-19: a study of 2579 patients.根据 COVID-19 严重程度的流行病学、耳鼻喉科、嗅觉和味觉结果:一项 2579 例患者的研究。
Eur Arch Otorhinolaryngol. 2021 Aug;278(8):2851-2859. doi: 10.1007/s00405-020-06548-w. Epub 2021 Jan 16.
9
Olfactory Dysfunction in COVID-19 Patients in a Tertiary Care Hospital; A Cross-Sectional Observational Study.三级护理医院中新冠病毒感染患者的嗅觉功能障碍;一项横断面观察研究。
Iran J Otorhinolaryngol. 2024 May;36(3):459-466. doi: 10.22038/IJORL.2024.76275.3557.
10
Olfactory and Gustatory Dysfunctions as a Clinical Manifestation of Coronavirus Disease 2019 in a Malaysian Tertiary Center.嗅觉和味觉障碍作为马来西亚一所 tertiary center 中 2019 冠状病毒疾病的临床特征。
Ann Otol Rhinol Laryngol. 2021 May;130(5):513-519. doi: 10.1177/0003489420963165. Epub 2020 Oct 7.

引用本文的文献

1
Cross-cultural modification of the University of Pennsylvania smell identification test for the Saudi Arabian population: Validation and normative values.宾夕法尼亚大学嗅觉识别测试在沙特阿拉伯人群中的跨文化修订:验证和常模值。
Saudi Med J. 2024 Jan;45(1):79-85. doi: 10.15537/smj.2024.45.1.20230422.
2
Olfactory and gustatory dysfunction, evaluation and the impact on quality of life among COVID-19 patients: a multi-centre study.新型冠状病毒肺炎患者嗅觉和味觉功能障碍、评估及其对生活质量的影响:一项多中心研究
Ann Med Surg (Lond). 2023 Sep 18;85(11):5403-5409. doi: 10.1097/MS9.0000000000001311. eCollection 2023 Nov.

本文引用的文献

1
Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Treat Post-COVID-19 Olfactory Impairment: A Multi-Center Double-Blinded Randomized Placebo- Controlled Clinical Trial.棕榈酸乙酯酰胺和叶黄素联合嗅觉训练治疗 COVID-19 后嗅觉障碍:一项多中心、双盲、随机安慰剂对照临床试验。
Curr Neuropharmacol. 2022;20(10):2001-2012. doi: 10.2174/1570159X20666220420113513.
2
Management of post-COVID-19 olfactory dysfunction.新冠后嗅觉功能障碍的管理
Curr Treat Options Allergy. 2022;9(1):1-18. doi: 10.1007/s40521-021-00297-9. Epub 2022 Jan 4.
3
Correlation of olfactory dysfunction with lung involvement and severity of COVID-19.
嗅觉功能障碍与 COVID-19 肺部受累及严重程度的相关性。
Ir J Med Sci. 2022 Aug;191(4):1843-1848. doi: 10.1007/s11845-021-02732-x. Epub 2021 Aug 10.
4
COVID-19: breaking down a global health crisis.COVID-19:破解一场全球健康危机。
Ann Clin Microbiol Antimicrob. 2021 May 18;20(1):35. doi: 10.1186/s12941-021-00438-7.
5
Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection.用于严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)/COVID-19 检测的工具和技术。
Clin Microbiol Rev. 2021 May 12;34(3). doi: 10.1128/CMR.00228-20. Print 2021 Jun 16.
6
Taste and Smell Impairment in Critically Ill Patients With COVID-19: An Intensive Care Unit Study.COVID-19 重症患者的味觉和嗅觉障碍:一项重症监护室研究。
Ear Nose Throat J. 2021 Apr;100(2_suppl):174S-179S. doi: 10.1177/0145561320977464. Epub 2020 Dec 1.
7
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.K18-hACE2 小鼠中的 COVID-19 治疗和发病机制,包括嗅觉丧失。
Nature. 2021 Jan;589(7843):603-607. doi: 10.1038/s41586-020-2943-z. Epub 2020 Nov 9.
8
Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran.伊朗新冠疫情与嗅觉功能障碍爆发的巧合。
Med J Islam Repub Iran. 2020 Jun 15;34:62. doi: 10.34171/mjiri.34.62. eCollection 2020.
9
Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered.嗅觉丧失:对其在 COVID-19 中的重要性的认识的演变,以及仍有待回答的问题。
Eur Arch Otorhinolaryngol. 2021 Jul;278(7):2187-2191. doi: 10.1007/s00405-020-06285-0. Epub 2020 Sep 9.
10
Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review.SARS-CoV-2 病毒的临床、分子和流行病学特征与 2019 年冠状病毒病(COVID-19):全面文献复习。
Diagn Microbiol Infect Dis. 2020 Sep;98(1):115094. doi: 10.1016/j.diagmicrobio.2020.115094. Epub 2020 May 30.