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沙特阿拉伯一家三级医院中新冠肺炎患者嗅觉功能障碍的发生率

Incidence of Olfactory Dysfunction in Patients with COVID-19 in a Tertiary Hospital in Saudi Arabia.

作者信息

Alfallaj Rayan, AlSkait Ghada, Alamari Nouf, Alfawzan Lama, Abualgasem Mohammed, Alotaibi Naif H, Sumaily Ibrahim, Alarifi Ibrahim, Alsaleh Saad

机构信息

Otolaryngology-Head & Neck Surgery Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Allergy Rhinol (Providence). 2022 Nov 25;13:21526575221140809. doi: 10.1177/21526575221140809. eCollection 2022 Jan-Dec.

Abstract

BACKGROUND

Coronavirus disease (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2, a novel virus that emerged in China in December 2019. In many cases of COVID-19, olfactory dysfunction (OD) is the only symptom.

OBJECTIVES

This study aimed to examine the incidence of OD in patients with COVID-19 and identify an association between OD and COVID-19-related morbidity and admission.

DESIGN

This was a cross-sectional study.

METHODS

Real-time reverse transcription polymerase chain reaction-confirmed cases of COVID-19 from the Security Forces Hospital electronic registry from June 2020 to September 2020 were included in our study. Data on medical background, severity of the disease, and other related factors were collected through phone calls and electronic healthcare systems and analyzed to investigate OD in the participants.

RESULTS

Of the participants, 68% had OD, with a mean recovery time of 18 days and a mean follow-up time of 129 days (76-211 days). OD was negatively correlated with admission and morbidity.

CONCLUSION

OD is a common presentation of COVID-19 and is more prevalent in mild cases of infection.

摘要

背景

冠状病毒病(COVID-19)由严重急性呼吸综合征冠状病毒2引起,这是一种于2019年12月在中国出现的新型病毒。在许多COVID-19病例中,嗅觉功能障碍(OD)是唯一症状。

目的

本研究旨在调查COVID-19患者中OD的发生率,并确定OD与COVID-19相关发病率及入院情况之间的关联。

设计

这是一项横断面研究。

方法

我们的研究纳入了2020年6月至2020年9月安全部队医院电子登记册中经实时逆转录聚合酶链反应确诊的COVID-19病例。通过电话和电子医疗系统收集有关医疗背景、疾病严重程度及其他相关因素的数据,并进行分析以调查参与者的OD情况。

结果

参与者中,68%有OD,平均恢复时间为18天,平均随访时间为129天(76 - 211天)。OD与入院及发病率呈负相关。

结论

OD是COVID-19的常见表现,在轻度感染病例中更为普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb90/9703475/57b4114a3623/10.1177_21526575221140809-fig1.jpg

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