Kokje Vivianne, De Vito Claudio, Varela Flavia Costa, Monnier Yan, Dulguerov Nicolas, Becker Minerva, Mermod Maxime
Department of Otorhinolaryngology-Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland.
Division of Clinical Pathology, Diagnostic Department, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland.
Radiol Case Rep. 2022 Nov 28;18(2):591-595. doi: 10.1016/j.radcr.2022.11.018. eCollection 2023 Feb.
Rosai-Dorfman disease is a non-Langherans cell histiocytosis typically revealed by lymphadenopathy. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. Few reports have described laryngeal lesions. We report the case of a Rosai-Dorfman disease in a 27-year-old female, presenting as an obstructing transglottic mass. We provide the results of the MRI and PET-scanner examination. As the treatment relies on surgical excision and the diagnosis depends on pathological examination, we also detail the analysis results that followed the surgical resection. This report highlights the necessity to consider Rosai-Dorfman disease as a potential diagnosis in case of a laryngeal submucosal mass.
罗萨伊-多夫曼病是一种非朗格汉斯细胞组织细胞增生症，通常表现为淋巴结病。结外受累发生率为43%，最常见于头颈部、皮肤和骨骼。关于喉部病变的报道很少。我们报告一例27岁女性的罗萨伊-多夫曼病，表现为阻塞性声门肿物。我们提供了MRI和PET扫描检查结果。由于治疗依赖手术切除且诊断取决于病理检查，我们还详细介绍了手术切除后的分析结果。本报告强调，对于喉部黏膜下肿物，有必要将罗萨伊-多夫曼病作为一种可能的诊断加以考虑。
