You Qian, Bai Ding-Xi, Wu Chen-Xi, Chen Huan, Hou Chao-Ming, Gao Jing
School of Nursing, Chengdu University of Traditional Chinese Medicine, China.
School of Nursing, Chengdu University of Traditional Chinese Medicine, China.
Asian Nurs Res (Korean Soc Nurs Sci). 2022 Dec;16(5):292-298. doi: 10.1016/j.anr.2022.11.002. Epub 2022 Nov 29.
Despite the high prevalence of postdialysis fatigue (PDF) in maintenance hemodialysis patients, no meta-analysis on the prevalence and risk factors of PDF has yet been published. This study aimed to identify the prevalence of PDF and explore its related factors.
PubMed, Embase, CENTRAL, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and the four Chinese databases (National Knowledge Infrastructure [CNKI], Chinese Biomedical Literature database [SinoMed], Wanfang Digital Periodicals [WANFANG], and Chinese Science and Technology Periodicals [VIP] database) were searched from inception up to July 2022. This study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The articles were independently searched by two reviewers, and the relevant data were extracted. The Agency for Healthcare Research and Quality was used to assess the quality of the included studies.
Thirteen articles with 2,118 participants were included. The pooled prevalence was 60.0%. The meta-analysis results revealed that the ultrafiltration volume, mean arterial pressure after dialysis, and good sleep quality were potentially associated with PDF, whereas only good sleep quality (odds ratio 0.24, 95% confidence interval 0.19-0.30) was significantly associated with PDF.
PDF is common in maintenance hemodialysis patients, which is related to the ultrafiltration volume, sleep quality, and mean arterial pressure after dialysis. However, the mechanism underlying the risk factors and PDF remains unknown. Further research is warranted to investigate the risk factors, intervention, treatment, and mechanism in maintenance hemodialysis patients.
尽管维持性血液透析患者中透析后疲劳（PDF）的患病率很高，但尚未发表关于PDF患病率和危险因素的荟萃分析。本研究旨在确定PDF的患病率并探讨其相关因素。
检索了PubMed、Embase、CENTRAL、Web of Science、护理及相关健康文献累积索引（CINAHL）以及四个中文数据库（中国知网[CNKI]、中国生物医学文献数据库[SinoMed]、万方数据期刊[WANFANG]和中国科技期刊[VIP]数据库），检索时间从建库至2022年7月。本研究按照系统评价和荟萃分析的首选报告项目指南进行。文章由两名 reviewers 独立检索，并提取相关数据。使用医疗保健研究与质量机构来评估纳入研究的质量。
纳入了13篇文章，共2118名参与者。合并患病率为60.0%。荟萃分析结果显示，超滤量、透析后平均动脉压和良好的睡眠质量可能与PDF有关，而只有良好的睡眠质量（优势比0.24，95%置信区间0.19 - 0.30）与PDF显著相关。
PDF在维持性血液透析患者中很常见，这与超滤量、睡眠质量和透析后平均动脉压有关。然而，危险因素与PDF之间的潜在机制仍不清楚。有必要进一步研究维持性血液透析患者的危险因素、干预措施、治疗方法及机制。
