Lorén J G, Guinea J
Rev Esp Fisiol. 1978 Sep;34(3):247-52.
Serratia marcescens is an enterobacteria which produces a characteristic red pigment denominated prodigiosin. To study the effect of glucose on the kinetics of this secondary metabolite, cultures of Serratia marcescens S10 were incubated at 30 degrees C in the mineral medium GL, with glucose (2 g/l) as the carbon source. Prodigiosin production in relation to glucose consumption is studied, and parallel-wise, the effect of various concentrations of glucose on prodigiosin production. The kinetics data show the close correlation between glucose consumption and the synthesis of prodigiosin. This substrate inhibits the synthesis of pigment in cultures grown on solid medium GL with concentrations of glucose up to 15 g/l.
粘质沙雷氏菌是一种肠杆菌,可产生一种名为灵菌红素的特征性红色色素。为了研究葡萄糖对这种次生代谢产物动力学的影响,将粘质沙雷氏菌S10培养物在30℃下于以葡萄糖(2 g/l)作为碳源的矿物培养基GL中培养。研究了灵菌红素产生与葡萄糖消耗的关系,同时还研究了不同浓度葡萄糖对灵菌红素产生的影响。动力学数据表明葡萄糖消耗与灵菌红素合成之间存在密切相关性。在固体培养基GL上生长的培养物中,该底物在葡萄糖浓度高达15 g/l时会抑制色素的合成。