Yao Chao-Yi, de Silva A Prasanna
School of Chemistry and Chemical Engineering, Queen's University, Belfast, BT9 5AG, Ireland.
Chempluschem. 2023 Apr;88(4):e202200362. doi: 10.1002/cplu.202200362. Epub 2022 Dec 1.
The general tool of fluorescent PET (photoinduced electron transfer) sensors/switches - a molecular design principle with engineering features - is outlined, with the aid of frontier orbital energy diagrams. Fluorophores such as anthracene, 1,3-diaryl-Δ -pyrazolines and 4-amino-1,8-naphthalimides are employed within this system, alongside receptors such as amines, carboxylates, crown ethers and amino acids. This tool appealed to a multinational corporation for building a medical analyzer for electrolytes such as Na , K , Ca and gases like CO , which became a commercially successful application. Finally, the tool was a springboard for chemistry to cross into computer science. The field of molecular logic can elucidate how molecules inside us handle information. Molecular examples of the simplest logic gates such as YES, NOT, OR, AND are described. A case of a human-level computation - visual edge detection - is also included.
借助前沿轨道能量图，概述了荧光正电子发射断层扫描（光致电子转移）传感器/开关的通用工具——一种具有工程特性的分子设计原理。该系统采用了诸如蒽、1,3 - 二芳基 - Δ - 吡唑啉和4 - 氨基 - 1,8 - 萘二甲酰亚胺等荧光团，以及诸如胺、羧酸盐、冠醚和氨基酸等受体。该工具吸引了一家跨国公司用于制造用于检测诸如Na⁺、K⁺、Ca²⁺等电解质以及CO₂等气体的医学分析仪，这成为了一个商业上成功的应用。最后，该工具成为了化学跨界进入计算机科学的跳板。分子逻辑领域可以阐明我们体内的分子是如何处理信息的。描述了诸如“是”“非”“或”“与”等最简单逻辑门的分子实例。还包括一个人类水平计算的案例——视觉边缘检测。
