Magri David C
Laboratory of Molecular Logic Gates, Department of Chemistry, Faculty of Science, University of Malta, Msida, Malta.
Front Chem. 2024 Apr 18;12:1393308. doi: 10.3389/fchem.2024.1393308. eCollection 2024.
The concept of a lab-on-a-molecule, which was proposed just short of two decades ago, has captured the imagination of scientists. From originally being proposed as an AND logic gate driven by three chemical inputs as a direct way of detecting congregations of chemical species, the definition of what constitutes a lab-on-a-molecule has broadened over the years. In this review, molecules that can detect multiple analytes by fluorescence, among other techniques, are reviewed and discussed, in the context of molecular logic and multi-analyte sensing. The review highlights challenges and suggestions for moving the frontiers of research in this field to the next dimension.
大约20年前提出的“分子上的实验室”概念激发了科学家们的想象力。最初它被提议作为一种由三种化学输入驱动的“与”逻辑门，作为检测化学物种聚集的直接方法，多年来，“分子上的实验室”的定义已经扩大。在这篇综述中，在分子逻辑和多分析物传感的背景下，对能够通过荧光及其他技术检测多种分析物的分子进行了综述和讨论。该综述强调了将该领域的研究前沿推进到新维度所面临的挑战和建议。
