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Does immune cell exhaustion lie at the heart of BCG-unresponsive disease?

作者信息

Ingersoll Molly A

机构信息

Université Paris Cité, Institut Cochin, INSERM U1016, Paris, France.

Department of Immunology, Institut Pasteur, Paris, France.

出版信息

Nat Rev Urol. 2023 Apr;20(4):201-202. doi: 10.1038/s41585-022-00687-x.

DOI:10.1038/s41585-022-00687-x
PMID:36456853
Abstract
摘要

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本文引用的文献

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Elevated T-cell Exhaustion and Urinary Tumor DNA Levels Are Associated with Bacillus Calmette-Guérin Failure in Patients with Non-muscle-invasive Bladder Cancer.高 T 细胞耗竭和尿肿瘤 DNA 水平与非肌肉浸润性膀胱癌患者卡介苗失败相关。
Eur Urol. 2022 Dec;82(6):646-656. doi: 10.1016/j.eururo.2022.09.008. Epub 2022 Oct 7.
2
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer.NKG2A 和 HLA-E 定义了膀胱癌中的另一种免疫检查点轴。
Cancer Cell. 2022 Sep 12;40(9):1027-1043.e9. doi: 10.1016/j.ccell.2022.08.005.
3
The impact of biological sex on diseases of the urinary tract.
生物性别对尿路疾病的影响。
Mucosal Immunol. 2022 May;15(5):857-866. doi: 10.1038/s41385-022-00549-0. Epub 2022 Jul 22.
4
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight.对非肌肉浸润性膀胱癌进行分层分子谱分析可增强生物学、临床和治疗方面的认识。
Cell Rep Med. 2021 Dec 21;2(12):100472. doi: 10.1016/j.xcrm.2021.100472.
5
100 years of Mycobacterium bovis bacille Calmette-Guérin.牛分枝杆菌卡介苗百年史。
Lancet Infect Dis. 2022 Jan;22(1):e2-e12. doi: 10.1016/S1473-3099(21)00403-5. Epub 2021 Sep 7.
6
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer.一种整合的多组学分析方法确定了非肌肉浸润性膀胱癌的预后分子亚型。
Nat Commun. 2021 Apr 16;12(1):2301. doi: 10.1038/s41467-021-22465-w.
7
BCG-unresponsive high-grade non-muscle invasive bladder cancer: what does the practicing urologist need to know?BCG 无应答的高级别非肌肉浸润性膀胱癌:临床泌尿科医生需要了解什么?
World J Urol. 2021 Nov;39(11):4037-4046. doi: 10.1007/s00345-021-03666-w. Epub 2021 Mar 27.
8
Mechanisms of BCG immunotherapy and its outlook for bladder cancer.BCG 免疫疗法的机制及其在膀胱癌中的展望。
Nat Rev Urol. 2018 Oct;15(10):615-625. doi: 10.1038/s41585-018-0055-4.
9
Genome plasticity of BCG and impact on vaccine efficacy.卡介苗的基因组可塑性及其对疫苗效力的影响。
Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5596-601. doi: 10.1073/pnas.0700869104. Epub 2007 Mar 19.
10
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors.腔内卡介苗治疗浅表性膀胱肿瘤
J Urol. 1976 Aug;116(2):180-3. doi: 10.1016/s0022-5347(17)58737-6.