The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Department of Nephrology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
BMC Cardiovasc Disord. 2022 Dec 2;22(1):513. doi: 10.1186/s12872-022-02946-6.
To evaluate the value of the ACEF II score in predicting postoperative hospital death and acute kidney injury requiring dialysis (AKI-D) in Chinese patients.
This retrospective study included adult patients who underwent cardiopulmonary bypass open heart surgery between January 2010 and December 2015 at Guangdong Provincial People's Hospital. ACEF II was evaluated to predict in-hospital death and AKI-D using the Hosmer-Lemeshow goodness of fit test for calibration and area under the receiver operating characteristic (ROC) curve for discrimination in non-elective and elective cardiac surgery.
A total of 9748 patients were included. Among them, 1080 underwent non-elective surgery, and 8615 underwent elective surgery. Mortality was 1.8% (177/9748). In elective surgery, the area under the ROC (AUC) of the ACEF II score was 0.704 (95% CI: 0.648-0.759), similar to the ACEF score of 0.709 (95% CI: 0.654-0.763). In non-elective surgery, the AUC of the ACEF II score was 0.725 (95% CI: 0.663-0.787), higher than the ACEF score (AUC = 0.625, 95% CI: 0.553-0.697). The incidence of AKI-D was 3.5% (345/9748). The AUC of the ACEF II score was 0.718 (95% CI: 0.687-0.749), higher than the ACEF score (AUC = 0.626, 95% CI: 0.594-0.658).
ACEF and ACEF II have poor discrimination ability in predicting AKI-D in non-elective surgery. The ACEF II and ACEF scores have the same ability to predict in-hospital death in elective cardiac surgery, and the ACEF II score is better in non-elective surgery. The ACEF II score can be used to assess the risk of AKI-D in elective surgery in Chinese adults.
评估 ACEF II 评分在中国患者中预测体外循环心脏手术后院内死亡和需要透析的急性肾损伤(AKI-D)的价值。
本回顾性研究纳入了 2010 年 1 月至 2015 年 12 月期间在广东省人民医院接受体外循环开胸心脏手术的成年患者。采用 Hosmer-Lemeshow 拟合优度检验评估 ACEF II 评分在非择期和择期心脏手术中的校准能力,以及受试者工作特征(ROC)曲线下面积(AUC)来预测院内死亡和 AKI-D。
共纳入 9748 例患者,其中 1080 例接受非择期手术,8615 例接受择期手术。死亡率为 1.8%(177/9748)。在择期手术中,ACEF II 评分的 ROC 曲线下 AUC 为 0.704(95% CI:0.648-0.759),与 ACEF 评分(0.709,95% CI:0.654-0.763)相似。在非择期手术中,ACEF II 评分的 AUC 为 0.725(95% CI:0.663-0.787),高于 ACEF 评分(AUC=0.625,95% CI:0.553-0.697)。AKI-D 的发生率为 3.5%(345/9748)。ACEF II 评分的 AUC 为 0.718(95% CI:0.687-0.749),高于 ACEF 评分(AUC=0.626,95% CI:0.594-0.658)。
ACEF 和 ACEF II 评分在预测非择期手术中 AKI-D 方面的鉴别能力较差。ACEF II 和 ACEF 评分在择期心脏手术中预测院内死亡的能力相同,而 ACEF II 评分在非择期手术中更好。ACEF II 评分可用于评估中国成人择期手术中 AKI-D 的风险。