Li Yanzi, Wang Zhi, Liu Junhui, Han Jianfeng, Yang Lin
Department of Medical Administration, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Department of Infectious surgery, Xi'an 8 Hospital, Xi'an, China.
Arch Med Sci. 2022 Nov 7;18(6):1678-1682. doi: 10.5114/aoms/155114. eCollection 2022.
This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant.
We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant.
The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group.
The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance.
本研究旨在调查感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）野生型毒株和德尔塔变异株患者的临床特征及疫苗有效性。
我们对感染SARS-CoV-2野生型毒株和德尔塔变异株的患者进行了回顾性评估。
德尔塔变异株组在未成年人中的感染率更高，这些未成年人嗅觉丧失或味觉障碍的发生率更高，潜伏期更短。未接种疫苗的患者出现严重分级的风险比接种疫苗的患者高15.59倍。德尔塔变异株组的病毒清除时间明显更短。
德尔塔变异株组显示出更高的传播性，接种疫苗可降低严重分级的发生率并促进病毒清除。
