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如果药物在全球范围内停止销售,在哪里可以获得继续治疗所需的药剂师制剂?一例需要使用肌苷酸钠治疗的 10 岁亚急性硬化性全脑炎(SSPE)患儿的案例报告。

Place of magistral preparations to continue the treatment if the drug is commercially stopped worldwide? A case report of a 10-year-old child with subacute sclerosing panencephalitis (SSPE) requiring inosiplex.

机构信息

Pharmacy Department, Grenoble University Hospital, Grenoble, France.

Pediatric Neurology Unit, Grenoble University Hospital, Grenoble, France.

出版信息

Emerg Microbes Infect. 2023 Dec;12(1):2148563. doi: 10.1080/22221751.2022.2148563.

Abstract

Subacute sclerosing panencephalitis (SSPE) is a late-onset and fatal viral disease caused by persistent infection of the central nervous system by measles virus (MeV). We present the case of a 10-year-old child from South Asia affected by SSPE, stabilized with a combination of intrathecal interferon-α2b (INF-α2b) injections and oral inosiplex and how we continued the treatment when inosiplex was commercially stopped worldwide.

摘要

亚急性硬化性全脑炎(SSPE)是一种迟发性和致命的病毒性疾病,由麻疹病毒(MeV)持续感染中枢神经系统引起。我们报告了一例来自南亚的 10 岁儿童 SSPE 病例,通过鞘内注射干扰素-α2b(INF-α2b)和口服肌苷的联合治疗得到稳定,以及在肌苷在全球范围内停止供应时我们如何继续进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a28/9788679/3a887f55e122/TEMI_A_2148563_F0001_OC.jpg

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