Pharmacy Department, Grenoble University Hospital, Grenoble, France.
Pediatric Neurology Unit, Grenoble University Hospital, Grenoble, France.
Emerg Microbes Infect. 2023 Dec;12(1):2148563. doi: 10.1080/22221751.2022.2148563.
Subacute sclerosing panencephalitis (SSPE) is a late-onset and fatal viral disease caused by persistent infection of the central nervous system by measles virus (MeV). We present the case of a 10-year-old child from South Asia affected by SSPE, stabilized with a combination of intrathecal interferon-α2b (INF-α2b) injections and oral inosiplex and how we continued the treatment when inosiplex was commercially stopped worldwide.
亚急性硬化性全脑炎(SSPE)是一种迟发性和致命的病毒性疾病,由麻疹病毒(MeV)持续感染中枢神经系统引起。我们报告了一例来自南亚的 10 岁儿童 SSPE 病例,通过鞘内注射干扰素-α2b(INF-α2b)和口服肌苷的联合治疗得到稳定,以及在肌苷在全球范围内停止供应时我们如何继续进行治疗。