University of Missouri Veterinary Health Center, Columbia, Missouri, USA.
Vet Surg. 2023 Feb;52(2):315-329. doi: 10.1111/vsu.13912. Epub 2022 Dec 2.
To report the management and outcomes of dogs treated for lower esophageal sphincter achalasia-like syndrome (LES-AS) with modified Heller myotomy, Dor fundoplication, and with the use of a temporary gastrostomy tube.
Retrospective.
Thirteen client-owned dogs.
Medical records and a client survey were used to assess frequency of vomiting/regurgitation, quality of life (QoL), bodyweight, and feeding modifications at the following time points: prior to referral, postoperatively from discharge to first recheck (4-6 weeks), and from first recheck to survey (48 months). Postoperative and gastrostomy tube complications were surveyed and recorded. Pretreatment and 4-6 weeks postoperative videofluoroscopic swallow studies (VFSS) were compared. Two-sided t-tests were used to compare outcomes between survey time points.
Postoperative VFSS scores (available in 9 dogs) improved over preoperative scores in 6 dogs, and 12/13 dogs survived to discharge. One dog was euthanized 3 days postoperatively due to aspiration pneumonia. Postoperative gastrostomy tube complications occurred in half of the dogs that survived to discharge. According to the owners, scores assigned to vomiting/regurgitation improved by 180% (P = .004), QoL by 100% (P = .004), and bodyweight by 63% (P = .035).
Modified Heller myotomy with Dor fundoplication and the use of a temporary gastrostomy tube improved clinical signs and owners' perceived quality of life in half of the dogs treated for LES-AS in our clinical setting. Oral sildenafil therapy discontinued postoperatively suggests that surgery was equally efficacious.
Modified Heller myotomy with Dor fundoplication and temporary gastrostomy tube is a treatment option with potentially sustained benefits for dogs that have LES-AS.
报告采用改良的 Heller 肌切开术、Dor 胃底折叠术,并使用临时胃造口管治疗犬下食管括约肌失弛缓症样综合征(LES-AS)的管理和结果。
回顾性研究。
13 只患犬。
使用病历和客户调查评估以下时间点的呕吐/反流频率、生活质量(QoL)、体重和喂养方式的改变:转诊前、手术后出院至第一次复查(4-6 周)和第一次复查至调查(48 个月)。调查并记录术后和胃造口管并发症。比较术前和 4-6 周时的视频荧光透视吞咽研究(VFSS)。使用双侧 t 检验比较各时间点的结果。
9 只犬中 6 只的术后 VFSS 评分较术前有所改善,13 只犬中 12 只存活至出院。一只狗术后 3 天因吸入性肺炎而被安乐死。存活至出院的狗中有一半出现术后胃造口管并发症。根据主人的说法,呕吐/反流评分提高了 180%(P=0.004),生活质量提高了 100%(P=0.004),体重增加了 63%(P=0.035)。
在我们的临床环境中,采用改良的 Heller 肌切开术联合 Dor 胃底折叠术和临时胃造口管治疗犬下食管括约肌失弛缓症样综合征可改善一半患犬的临床症状和主人对生活质量的感知。术后停用口服西地那非提示手术同样有效。
改良的 Heller 肌切开术联合 Dor 胃底折叠术和临时胃造口管是治疗下食管括约肌失弛缓症样综合征的一种选择,具有潜在的持续益处。