Brown P, Cathala F, Gajdusek D C
Rev Neurol (Paris). 1978 Apr;134(4):277-86.
The virus of Creutzfeldt Jakob disease differs from conventional viruses in its extraordinary resistance to commonly used physical and chemical methods of decontamination. Autoclaving the virus for 1 hour at 121 degrees C and 2 atmospheres pressure is the most certain means for achieving total inactivation. Exposure to 5 p. 100 hypochlorite for several hours can also totally inactivate the virus, and exposure to phenol or potassium permanganate is probably effective, but as yet insufficiently tested.
克雅氏病病毒与传统病毒不同,它对常用的物理和化学去污方法具有极强的抵抗力。在121摄氏度和2个大气压下对病毒进行1小时高压灭菌是实现完全灭活的最可靠方法。将病毒暴露于5%的次氯酸盐中数小时也可使其完全灭活,暴露于苯酚或高锰酸钾可能有效,但尚未经过充分测试。