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[克雅氏病。患者管理和诊断程序的推荐预防措施(作者译)]

[Creutzfeldt Jakob disease. Recommended precautions for patient management and diagnostic procedures (author's transl)].

作者信息

Brown P, Cathala F, Gajdusek D C

出版信息

Rev Neurol (Paris). 1978 Apr;134(4):277-86.

PMID:364589
Abstract

The virus of Creutzfeldt Jakob disease differs from conventional viruses in its extraordinary resistance to commonly used physical and chemical methods of decontamination. Autoclaving the virus for 1 hour at 121 degrees C and 2 atmospheres pressure is the most certain means for achieving total inactivation. Exposure to 5 p. 100 hypochlorite for several hours can also totally inactivate the virus, and exposure to phenol or potassium permanganate is probably effective, but as yet insufficiently tested.

摘要

克雅氏病病毒与传统病毒不同,它对常用的物理和化学去污方法具有极强的抵抗力。在121摄氏度和2个大气压下对病毒进行1小时高压灭菌是实现完全灭活的最可靠方法。将病毒暴露于5%的次氯酸盐中数小时也可使其完全灭活,暴露于苯酚或高锰酸钾可能有效,但尚未经过充分测试。

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