Zhou Chi, Xia Zongyi, Chen Bing, Song Yanxu, Lian Zhexun
Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Am J Cardiol. 2023 Jan 15;187:100-109. doi: 10.1016/j.amjcard.2022.10.038. Epub 2022 Nov 29.
Few researchers have discussed the differences in gender between the age groups of patients who underwent transcatheter aortic valve implantation (TAVI). We searched the National Readmissions Database from 2012 to 2019 to identify adults who underwent TAVI. We studied hospital outcomes and short- to medium-term outcomes by age stratification (18 to 59, 60 to 69, 70 to 79, and 80 to 90 years) after TAVI and categorized by gender. We included 147,481 patients who underwent TAVI, and 54,802 pairs were matched using propensity score matching separately for each age group. Compared with men, women in all age groups had a similar rate of hospital death. Except the 18- to 59-year-old groups, female patients were less likely to undergo permanent pacemaker implantation and transfusion. Records of readmission at 30 days and 6 months were used as the follow-up outcome according to the presence or absence of readmission. Major adverse cardiovascular events (MACEs) were a composite of cardiovascular readmission, all-cause mortality during readmission, and stroke readmission. At the 30-day follow-up visit, there was no difference in the all-cause readmission and MACE between women and men in any group. At the 6-month follow-up visit, women in the 70- to 79-year-old and 80- to 90-year-old groups had a high risk of all-cause readmission. In conclusion, we reported that female patients have similar in-hospital death rates to male patients who underwent TAVI. During the 30-day follow-up visit, the all-cause readmission and MACE were not different in all age groups between men and women. At 6 months, women in the 70- to 79-year-old and 80- to 90-year-old groups had a higher risk of all-cause readmission.
很少有研究人员讨论过接受经导管主动脉瓣植入术（TAVI）的患者年龄组之间的性别差异。我们检索了2012年至2019年的国家再入院数据库，以确定接受TAVI的成年人。我们按年龄分层（18至59岁、60至69岁、70至79岁和80至90岁）研究了TAVI术后的医院结局以及短期至中期结局，并按性别进行分类。我们纳入了147481例接受TAVI的患者，并针对每个年龄组分别使用倾向评分匹配法匹配了54802对。与男性相比，所有年龄组的女性医院死亡率相似。除了18至59岁年龄组外，女性患者接受永久性起搏器植入和输血的可能性较小。根据是否再次入院，将30天和6个月时的再入院记录用作随访结局。主要不良心血管事件（MACE）包括心血管再入院、再入院期间的全因死亡率和中风再入院。在30天的随访中，任何组的女性和男性在全因再入院和MACE方面均无差异。在6个月的随访中，70至79岁和80至90岁年龄组的女性全因再入院风险较高。总之，我们报告称，接受TAVI的女性患者与男性患者的院内死亡率相似。在30天的随访中，所有年龄组的男性和女性在全因再入院和MACE方面均无差异。在6个月时，70至79岁和80至90岁年龄组的女性全因再入院风险较高。
