Laboratory of Microbiology, Wageningen University and Research, Wageningen, the Netherlands; Scope Biosciences B.V., Wageningen, the Netherlands.
Laboratory of Microbiology, Wageningen University and Research, Wageningen, the Netherlands.
Mol Cell. 2022 Dec 1;82(23):4405-4406. doi: 10.1016/j.molcel.2022.11.007.
In this issue, Liu et al. present an in-depth study aiming to unravel the structural, biochemical, and physiological aspects of how type III-E CRISPR-Cas systems trigger abortive infection by activating a protease upon target RNA recognition..
在本期中,Liu 等人进行了一项深入研究,旨在揭示 III-E 型 CRISPR-Cas 系统如何通过靶 RNA 识别后激活蛋白酶来触发无效感染,从而阐明其结构、生化和生理方面。