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Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study.肾脏功能指标与脑磁共振成像中小血管疾病和神经退行性病变标志物的相关性:社区动脉粥样硬化风险研究(ARIC)。
Am J Kidney Dis. 2023 Mar;81(3):261-269.e1. doi: 10.1053/j.ajkd.2022.07.013. Epub 2022 Sep 27.
2
Association Between Cerebral Cortical Microinfarcts and Perilesional Cortical Atrophy on 3T MRI.3T MRI 上皮质微梗死与皮质旁萎缩的相关性研究。
Neurology. 2022 Feb 8;98(6):e612-e622. doi: 10.1212/WNL.0000000000013140. Epub 2021 Dec 3.
3
Kidney Function Is Not Related to Brain Amyloid Burden on PET Imaging in The 90+ Study Cohort.在90岁及以上研究队列中,肾脏功能与PET成像上的脑淀粉样蛋白负荷无关。
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Sodium--glucose co-transporter-2 inhibitors for patients with diabetic and nondiabetic chronic kidney disease: a new era has already begun.钠-葡萄糖协同转运蛋白 2 抑制剂在糖尿病和非糖尿病慢性肾脏病患者中的应用:一个新的时代已经开始。
J Hypertens. 2021 Jun 1;39(6):1090-1097. doi: 10.1097/HJH.0000000000002776.
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Cystatin C, cognition, and brain MRI findings in 90+-year-olds.胱抑素 C、认知功能与 90 岁以上老年人的脑部 MRI 结果。
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Chronic Kidney Disease Increases Cerebral Microbleeds in Mouse and Man.慢性肾脏病增加小鼠和人类的脑微出血。
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8
The Cerebrovascular-Chronic Kidney Disease Connection: Perspectives and Mechanisms.脑血管病与慢性肾脏病的关联:观点与机制。
Transl Stroke Res. 2017 Feb;8(1):67-76. doi: 10.1007/s12975-016-0499-x. Epub 2016 Sep 14.
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Albuminuria, kidney function, and the incidence of cognitive impairment among adults in the United States.美国成年人的蛋白尿、肾功能与认知障碍发生率。
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Alzheimer morphology is not increased in dialysis-associated encephalopathy and long-term hemodialysis.在透析相关性脑病和长期血液透析中,阿尔茨海默病形态学并未增加。
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慢性肾脏病认知能力下降的新见解。

New insights into cognitive decline in chronic kidney disease.

机构信息

Division of Nephrology, Department of Medicine, University of California, Irvine, Orange, CA, USA.

Department of Neurology, University of California, Irvine, Orange, CA, USA.

出版信息

Nat Rev Nephrol. 2023 Apr;19(4):214-215. doi: 10.1038/s41581-022-00656-y.

DOI:10.1038/s41581-022-00656-y
PMID:36460897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10669749/
Abstract

Chronic kidney disease (CKD) is known to be associated with cognitive impairment, but the mechanisms that underlie this kidney–brain connection are unclear. A recent study provides evidence that CKD is an independent risk factor for cognitive decline due to cerebral small vessel disease.

摘要

慢性肾脏病(CKD)已知与认知障碍有关,但导致这种肾脏-大脑联系的机制尚不清楚。最近的一项研究提供了证据,表明 CKD 是由于脑小血管疾病导致认知能力下降的独立危险因素。