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法属西印度群岛灾难性的 COVID-19 Delta 变体激增:重症监护室分诊政策报告。

Catastrophic COVID-19 Delta Variant Surge in French West Indies: Report of an ICU Triage Policy.

机构信息

Réanimation Médicale et Chirurgicale, Centre Hospitalier universitaire de la Guadeloupe, Chemin Chauvel, Les Abymes, 97139 Guadeloupe, France.

Departement d'épidémiologie, Institut Pasteur de la Guadeloupe, Morne Jolivière, 97183 Abymes, France.

出版信息

Crit Care Med. 2023 Jan 1;51(1):57-68. doi: 10.1097/CCM.0000000000005707. Epub 2022 Nov 8.

Abstract

OBJECTIVES

Here, we report the management of a catastrophic COVID-19 Delta variant surge, which overloaded ICU capacity, using crisis standards of care (CSC) based on a multiapproach protocol.

DESIGN

Retrospective observational study.

SETTING

University Hospital of Guadeloupe.

PATIENTS

This study retrospectively included all patients who were hospitalized for COVID-19 pneumonia between August 11, 2021, and September 10, 2021, and were eligible for ICU admission.

INTERVENTION

Based on age, comorbidities, and disease severity, patients were assigned to three groups: Green (ICU admission as soon as possible), Orange (ICU admission after the admission of all patients in the Green group), and Red (no ICU admission).

MEASUREMENTS AND MAIN RESULTS

Among the 328 patients eligible for ICU admission, 100 (30%) were assigned to the Green group, 116 (35%) to the Orange group, and 112 (34%) to the Red group. No patient in the Green group died while waiting for an ICU bed, whereas 14 patients (12%) in the Orange group died while waiting for an ICU bed. The 90-day mortality rates were 24%, 37%, and 78% in the Green, Orange, and Red groups, respectively. A total of 130 patients were transferred to the ICU, including 79 from the Green group, 51 from the Orange group, and none from the Red group. Multivariate analysis revealed that among patients admitted to the ICU, death was independently associated with a longer time between ICU referral and ICU admission, the Sequential Organ Failure Assessment score, and the number of comorbidities, but not with triage group.

CONCLUSIONS

CSC based on a multiapproach protocol allowed admission of all patients with a good prognosis. Higher mortality was associated with late admission, rather than triage group.

摘要

目的

在此,我们报告了一种使用基于多方法协议的危重症标准护理(CSC)来管理灾难性 COVID-19 Delta 变体激增的情况,这种激增使 ICU 容量过载。

设计

回顾性观察性研究。

设置

瓜德罗普岛大学医院。

患者

这项研究回顾性纳入了所有在 2021 年 8 月 11 日至 9 月 10 日期间因 COVID-19 肺炎住院且符合 ICU 入院条件的患者。

干预

根据年龄、合并症和疾病严重程度,将患者分为三组:绿色(尽快入住 ICU)、橙色(绿色组所有患者入院后入住 ICU)和红色(不入住 ICU)。

测量和主要结果

在符合 ICU 入院条件的 328 名患者中,有 100 名(30%)被分配到绿色组,116 名(35%)被分配到橙色组,112 名(34%)被分配到红色组。在等待 ICU 床位期间,绿色组没有患者死亡,而在橙色组等待 ICU 床位期间有 14 名患者(12%)死亡。在绿色、橙色和红色组中,90 天死亡率分别为 24%、37%和 78%。共有 130 名患者转入 ICU,其中 79 名来自绿色组,51 名来自橙色组,红色组无一例患者转入。多变量分析显示,在转入 ICU 的患者中,死亡与 ICU 转介和 ICU 入院之间的时间延长、序贯器官衰竭评估评分以及合并症数量独立相关,但与分类组无关。

结论

基于多方法协议的 CSC 允许所有预后良好的患者入院。较高的死亡率与延迟入院有关,而不是分类组。

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