University of Illinois at Chicago, Department of Psychology, Chicago; University of Illinois at Chicago, Institute for Health Research & Policy, Chicago; University of Illinois at Chicago, Institute for Minority Health Research, Chicago; San Diego State University, Department of Psychology, San Diego, CA.
Hospital of the University of Pennsylvania, Department of Surgery, Philadelphia.
Ann Epidemiol. 2023 Feb;78:1-8. doi: 10.1016/j.annepidem.2022.11.003. Epub 2022 Dec 5.
Examine the association between neighborhood segregation and 6-year incident metabolic syndrome (MetSyn) in the Hispanic Community Health Study/Study of Latinos.
Prospective cohort of adults residing in Miami, Chicago, the Bronx, and San Diego. The analytic sample included 6,710 participants who did not have MetSyn at baseline. The evenness and exposure dimensions of neighborhood segregation, based on the Gini and Isolation indices, respectively, were categorized into quintiles (Q). Racialized economic concentration was measured with the Index of Concentration at the Extremes (continuously and Q).
Exposure, but not evenness, was associated with higher disease odds (Q1 (lower segregation) vs. Q4, OR = 1.53, 95% CI = 1.082.17; Q5, OR = 2.29, 95% CI = 1.493.52). Economic concentrationprivilege (continuous OR = 0.87, 95% CI = 0.770.98), racial concentrationracialized privilege (Q1 (greater concentration) vs. Q2 OR = 0.75, 95% CI = 0.541.04; Q3 OR = 0.68, 95% CI = 0.441.05; Q4 OR = 0.68, 95% CI = 0.451.01; Q5 OR = 0.64, 95% CI = 0.420.98)(continuous OR = 0.93, 95% CI = 0.821.04), and racialized economic concentrationprivilege (i.e., higher SES non-Hispanic White, continuous OR = 0.86, 95% CI = 0.760.98) were associated with lower disease odds.
Hispanics/Latino adults residing in neighborhoods with high segregation had higher risk of incident MetSyn compared to those residing in neighborhoods with low segregation. Research is needed to identify the mechanisms that link segregation to poor metabolic health.
在西班牙裔社区健康研究/拉丁裔研究中，检查邻里隔离与 6 年内发生代谢综合征（MetSyn）的关联。
这是一项居住在迈阿密、芝加哥、布朗克斯和圣地亚哥的成年人的前瞻性队列研究。分析样本包括基线时没有 MetSyn 的 6710 名参与者。根据基尼指数和隔离指数，将邻里隔离的均匀性和暴露维度分别分为五等份（Q）。种族经济集中程度通过极端集中指数（连续和 Q）来衡量。
仅暴露（而非均匀性）与更高的患病几率相关（Q1（较低的隔离）与 Q4 相比，OR=1.53，95%CI=1.082.17；Q5，OR=2.29，95%CI=1.493.52）。经济集中特权（连续 OR=0.87，95%CI=0.770.98），种族集中种族特权（Q1（更高的集中）与 Q2 相比，OR=0.75，95%CI=0.541.04；Q3 OR=0.68，95%CI=0.441.05；Q4 OR=0.68，95%CI=0.451.01；Q5 OR=0.64，95%CI=0.420.98）（连续 OR=0.93，95%CI=0.821.04），以及种族经济集中特权（即，较高的 SES 非西班牙裔白人，连续 OR=0.86，95%CI=0.760.98）与较低的患病几率相关。
与居住在低隔离社区的西班牙裔/拉丁裔成年人相比，居住在高隔离社区的成年人发生代谢综合征的风险更高。需要研究确定将隔离与不良代谢健康联系起来的机制。
