Weiner Lauren S, Nagel Stori, Irene Su H, Hurst Samantha, Levy Susan S, Arredondo Elva M, Hekler Eric, Hartman Sheri J
Herbert Wertheim School of Public Health and Human Longevity Science, UC San Diego, La Jolla, CA, USA.
UC San Diego Moores Cancer Center, 3855 Health Sciences Drive, La Jolla, CA, USA.
J Behav Med. 2023 Aug;46(4):578-593. doi: 10.1007/s10865-022-00381-8. Epub 2022 Dec 7.
Younger breast cancer survivors (YBCS) consistently report poorer quality of life (QOL) than older survivors. Increasing physical activity (PA) may improve QOL, but this has been understudied in YBCS. This single arm pilot study evaluated the feasibility and acceptability of a 3-month, peer-delivered, remote intervention to increase PA and improve QOL in YBCS. Data were collected from October 2019 - July 2020. Participants (n = 34, 43.1 ± 5.5 years old, 46 ± 34.4 months post-diagnosis, BMI = 30.2 ± 7.4 kg/m) completed six video sessions with a trained peer mentor; self-monitored PA with a Fitbit activity tracker; and interacted with a private Fitbit Community for social support. At baseline, 3-and 6-months, participants completed QOL questionnaires and PA was measured through accelerometer (moderate-to-vigorous PA [MVPA]) and self-report (strength and flexibility). A parallel mixed-methods approach (qualitative interviews and quantitative satisfaction survey at 3-months) explored intervention feasibility and acceptability. One-way repeated-measures ANOVAs examined impacts on PA and QOL at 3-and 6-months. The intervention was feasible as evidenced by efficient recruitment, high retention, and adherence to intervention components. Remote delivery, working with a peer mentor, and using Fitbit tools were highly acceptable. From baseline to 3-months, participants increased time spent in objectively measured MVPA, strength, and flexibility exercises, and reported meaningful improvements to body image, fatigue, anxiety, and emotional support. A fully remote, peer-to-peer intervention is an acceptable and promising strategy to increase PA and improve QOL in YBCS. Refinements to the intervention and its delivery should be further assessed in future studies, toward the goal of disseminating an evidence-based, scalable intervention to the growing number of YBCS.Trial registration Prospectively registered as NCT04064892.
较年轻的乳腺癌幸存者（YBCS）一直报告称其生活质量（QOL）比年长的幸存者更差。增加身体活动（PA）可能会改善生活质量，但在YBCS中对此研究不足。这项单臂试点研究评估了一项为期3个月、由同伴提供的远程干预措施在增加YBCS的身体活动和改善生活质量方面的可行性和可接受性。数据收集时间为2019年10月至2020年7月。参与者（n = 34，年龄43.1±5.5岁，确诊后46±34.4个月，体重指数= 30.2±7.4kg/m）与一名经过培训的同伴导师完成了六个视频课程；使用Fitbit活动追踪器进行自我监测身体活动；并与一个私人Fitbit社区互动以获得社会支持。在基线、3个月和6个月时，参与者完成生活质量问卷，并通过加速度计（中度至剧烈身体活动[MVPA]）和自我报告（力量和柔韧性）来测量身体活动。一种并行的混合方法（3个月时进行定性访谈和定量满意度调查）探讨了干预措施的可行性和可接受性。单向重复测量方差分析检验了3个月和6个月时对身体活动和生活质量的影响。该干预措施是可行的，有效招募、高留存率以及对干预组成部分的依从性证明了这一点。远程授课、与同伴导师合作以及使用Fitbit工具是非常可接受的。从基线到3个月，参与者增加了客观测量的MVPA、力量和柔韧性锻炼的时间，并报告称身体形象、疲劳、焦虑和情感支持有了有意义的改善。一项完全远程的同伴干预是一种可接受且有前景的策略，可增加YBCS的身体活动并改善其生活质量。未来的研究应进一步评估对干预措施及其实施的改进，目标是向越来越多的YBCS传播基于证据的、可扩展的干预措施。试验注册前瞻性注册为NCT04064892。
Zotero 插件