一项针对老年癌症幸存者的远程提供的低强度体育活动干预：可行性随机对照试验方案

A Remotely Delivered Light-Intensity Physical Activity Intervention for Older Cancer Survivors: Protocol for a Feasibility Randomized Controlled Trial.

作者信息

Blair Cindy K, Brown-Glaberman Ursa, Walters Scott T, Pestak Claire, Boyce Tawny, Barriga Laura, Burgess Ellen, Tawfik Bernard, Killough Cynthia, Kinney Anita Y, Demark-Wahnefried Wendy, Meisner Angela L, Wiggins Charles L, Pankratz V Shane, Davis Sally

机构信息

Department of Internal Medicine, University of New Mexico, Albuquerque, NM, United States.

University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, United States.

出版信息

JMIR Res Protoc. 2024 Dec 13;13:e59504. doi: 10.2196/59504.

DOI:10.2196/59504

PMID:39671575

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11681294/

Abstract

BACKGROUND

Older cancer survivors face age- and treatment-related comorbidities, including physical functional impairment, which are exacerbated by physical inactivity and sedentary behavior. Regular physical activity can reduce this risk, yet less than 30% of older cancer survivors meet the recommended guidelines for physical activity.

OBJECTIVE

This study aims to describe the design, methods, and rationale for a remotely delivered intervention that uses a whole-of-day approach to physical activity in older cancer survivors. This approach focuses on the accumulation of intermittent bouts of light-intensity activity throughout the entire day by disrupting and reducing sedentary activity. The intervention was guided by social cognitive and self-determination theories and incorporated motivational interviewing.

METHODS

The 12-week Move for Your Health trial randomly assigned 64 older cancer survivors to a theory-based physical activity intervention or a waitlist control. A Fitbit (Google) activity tracker and smartphone app were used to promote awareness of activity levels and enable self-monitoring of both activity and inactivity in tandem with health coaching phone calls. Motivational interviewing was used to engage participants and tailor strategies to achieve goals during the 12-week intervention. Data were collected at baseline, immediately after the intervention, and at longer-term follow-up (3 months thereafter). Feasibility outcomes included recruitment, retention, adherence, adverse events, and acceptability. Other outcomes included obtaining the parameter estimates for changes in physical function, physical performance, physical activity, sedentary behavior, and quality of life.

RESULTS

Recruitment for the Move for Your Health randomized controlled trial was completed in June 2023. Data collection was completed in March 2024. Data analyses are ongoing.

CONCLUSIONS

The results of this trial will provide information on the feasibility of implementing this intervention in the target patient population, as well as data that will provide information about the potential impact of the intervention on the outcomes. Both of these outcomes will inform the design of a larger randomized controlled trial to more fully test a physical activity intervention in an older cancer survivor population.

TRIAL REGISTRATION

ClinicalTrials.gov NCT05582889; https://clinicaltrials.gov/study/NCT05582889.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/59504.

摘要

背景

老年癌症幸存者面临与年龄和治疗相关的合并症，包括身体功能障碍，而身体不活动和久坐行为会加剧这些问题。定期进行体育活动可以降低这种风险，但只有不到30%的老年癌症幸存者达到体育活动的推荐指南。

目的

本研究旨在描述一种针对老年癌症幸存者的远程干预措施的设计、方法和基本原理，该干预措施采用全天体育活动方法。这种方法通过打破和减少久坐活动，专注于在一整天内积累间歇性的低强度活动。该干预以社会认知理论和自我决定理论为指导，并纳入了动机性访谈。

方法

为期12周的“为健康而运动”试验将64名老年癌症幸存者随机分为基于理论的体育活动干预组或候补对照组。使用Fitbit（谷歌）活动追踪器和智能手机应用程序来提高对活动水平的认识，并在健康指导电话的配合下实现对活动和不活动的自我监测。在为期12周的干预期间，使用动机性访谈来促使参与者参与并调整策略以实现目标。在基线、干预结束后立即以及长期随访（此后3个月）时收集数据。可行性结果包括招募、留存、依从性、不良事件和可接受性。其他结果包括获得身体功能、身体表现、体育活动、久坐行为和生活质量变化的参数估计值。