Departments of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Pediatr Blood Cancer. 2023 Feb;70(2):e30089. doi: 10.1002/pbc.30089. Epub 2022 Dec 10.
Social determinants of health (SDoH) may impact outcomes in sickle cell disease (SCD). We conducted a comprehensive literature review of five electronic databases to elucidate the relationship between SDoH and SCD, and identify gaps in the literature. Our search yielded 59 articles, which we organized into five SDoH areas: Neighborhood and Built Environment, Health and Healthcare, Social and Community Context, Education, and Economic Stability. We found that social determinants, such as access to healthcare, were inconsistently evaluated. Improved recognition and understanding of SDoH should enhance the development of programs that directly address its detrimental effects on patients with SCD.
社会决定因素(SDoH)可能会影响镰状细胞病(SCD)的结局。我们对五个电子数据库进行了全面的文献回顾,以阐明 SDoH 与 SCD 之间的关系,并确定文献中的空白。我们的搜索结果产生了 59 篇文章,我们将其组织成五个 SDoH 领域:邻里和建筑环境、健康和医疗保健、社会和社区环境、教育和经济稳定性。我们发现,社会决定因素,如获得医疗保健的机会,评估结果并不一致。提高对 SDoH 的认识和理解应有助于制定直接解决其对 SCD 患者不利影响的方案。