Hartl Stefan, Auf der Heiden Carsten, Bejinariu Alexandru, Clasen Lukas, Füting Anna, Vom Dahl Stephan, Lüdde Tom, Kelm Malte, Makimoto Hisaki
Department of Cardiology, Pulmonary Diseases and Vascular Medicine, Medical Faculty, Heinrich-Heine University, 40225 Düsseldorf, Germany.
Department of Electrophysiology, Alfried Krupp Hospital, 45131 Essen, Germany.
J Clin Med. 2022 Nov 23;11(23):6917. doi: 10.3390/jcm11236917.
Esophageal thermal lesions following pulmonary vein isolation (PVI) for atrial fibrillation (AF) potentially harbor lethal complications. Radiofrequency (RF)-PVI using contact force-technology can reduce collateral damage. We evaluated the incidence of endoscopically detected esophageal lesions (EDEL) and the contribution of contact force to esophageal lesion formation without esophageal temperature monitoring. One hundred and thirty-one AF patients underwent contact force-guided RF-PVI. Contact force, energy, force-time-integral, and force-power-time-integral were adopted. During PVI at the posterior segment of the wide antral circumferential line, limits were set for energy (30 W), duration (30 s) and contact force (40 g). Ablations were analyzed postero-superior and -inferior around PVs. Endoscopy within 120 h identified EDEL in six patients (4.6%). In EDEL(+), obesity was less frequent (17% vs. 68%, = 0.018), creatinine was higher (1.55 ± 1.18 vs. 1.07 ± 0.42 mg/dL, = 0.016), and exclusively at the left postero-inferior site, force-time-integral and force-power-time-integral were greater (2973 ± 3267 vs. 1757 ± 1262 g·s, = 0.042 and 83,547 ± 105,940 vs. 43,556 ± 35,255 g·J, = 0.022, respectively) as compared to EDEL(-) patients. No major complications occurred. At 12 months, arrhythmia-free survival was 74%. The incidence of EDEL was low after contact force-guided RF-PVI. Implementing combined contact force-indices on the postero-inferior site of left-sided PVs may reduce EDEL.
用于心房颤动(AF)的肺静脉隔离(PVI)术后的食管热损伤可能会引发致命并发症。使用接触力技术的射频(RF)-PVI可减少附带损伤。我们评估了内镜检测到的食管损伤(EDEL)的发生率以及在不进行食管温度监测的情况下接触力对食管损伤形成的影响。131例AF患者接受了接触力引导下的RF-PVI。采用了接触力、能量、力-时间积分和力-功率-时间积分。在宽环周线后段进行PVI期间,设定了能量(30W)、持续时间(30秒)和接触力(40g)的限制。对肺静脉周围的后上和后下消融进行了分析。120小时内的内镜检查发现6例患者(4.6%)存在EDEL。在EDEL(+)患者中,肥胖情况较少见(17%对68%,P = 0.018),肌酐水平较高(1.55±1.18对1.07±0.42mg/dL,P = 0.016),并且仅在左后下部位,与EDEL(-)患者相比,力-时间积分和力-功率-时间积分更大(分别为2973±3267对1757±1262g·s,P = 0.042和83547±105940对43556±35255g·J,P = 0.022)。未发生重大并发症。12个月时,无心律失常生存率为74%。接触力引导下的RF-PVI术后EDEL的发生率较低。在左侧肺静脉的后下部位实施联合接触力指标可能会降低EDEL。