Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA), Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus, Akademisches Lehrkrankenhaus der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany; Die Sektion Medizin, Universität zu Lübeck, Lübeck, Germany.
Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Academy For Arrhythmias (FAFA), Kardiologie, Medizinische Klinik III, Agaplesion Markus Krankenhaus, Akademisches Lehrkrankenhaus der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany.
Heart Rhythm. 2020 Nov;17(11):1833-1840. doi: 10.1016/j.hrthm.2020.05.029. Epub 2020 May 26.
High-power, short-duration ablation for pulmonary vein isolation (PVI) in the treatment of atrial fibrillation (AF) facilitates the procedure and improve effectiveness; however, esophageal injury remains a safety concern.
The purpose of this study was to investigate the role of luminal esophageal temperature (LET) monitoring during high-power ablation for PVI in terms of endoscopic esophageal lesion.
Patients with symptomatic AF underwent ablation index-guided high-power (AI-HP) PVI (50 W; AI anterior wall/posterior wall: 550/400). In the first consecutive set of patients, an insulated esophageal temperature probe was used for LET monitoring (cutoff LET >39°C) (group A). In the second consecutive set of patients, the probe was not used (group B). All patients were scheduled to undergo esophageal endoscopy 1-3 days after ablation.
A total of 120 patients (60 group A; 60 group B) were included in the study (mean age 67.8 years; 64% male). Baseline characteristics and procedural outcomes were similar between the 2 groups. Procedural PVI was achieved in all patients. First-pass PVI rate was 96.6%. Mean procedural radiofrequency (RF) time was 11.5 minutes, mean procedural time was 55.5 minutes, and fluoroscopic time was 5.6 minutes. Mean contact force at the LA posterior wall was 23 g, and mean RF ablation time at the LA posterior wall was 3.2 minutes. Two patients in group A and 1 patient in group B had endoscopic small esophageal lesions (P = .99). No serious procedural adverse events were observed.
Among patients undergoing AI-HP (50 W) PVI, the incidences of ablation-related endoscopic esophageal lesion in patients with and those without use of a temperature probe for LET monitoring (cutoff 39°C) were comparably low.
肺静脉隔离(PVI)的高功率、短时间消融治疗心房颤动(AF)可简化手术并提高疗效,但食管损伤仍是一个安全隐患。
本研究旨在探讨高功率消融期间管腔内食管温度(LET)监测在 PVI 中的作用,以评估内镜下食管病变。
接受消融指数指导的高功率(AI-HP)PVI(50 W;AI 前壁/后壁:550/400)治疗的有症状 AF 患者。在第一组连续患者中,使用隔热食管温度探头进行 LET 监测(截定点 LET>39°C)(A 组)。在第二组连续患者中,不使用探头(B 组)。所有患者均在消融后 1-3 天行食管内镜检查。
共纳入 120 例患者(A 组 60 例,B 组 60 例)(平均年龄 67.8 岁,64%为男性)。两组间基线特征和手术结果相似。所有患者均成功完成 PVI 消融。初次 PVI 成功率为 96.6%。平均手术射频(RF)时间为 11.5 分钟,平均手术时间为 55.5 分钟,透视时间为 5.6 分钟。左心房后壁的平均接触力为 23 g,左心房后壁的平均 RF 消融时间为 3.2 分钟。A 组中有 2 例和 B 组中有 1 例患者内镜下发现小的食管病变(P=0.99)。未观察到严重的手术不良事件。
在接受 AI-HP(50 W)PVI 的患者中,使用和不使用 LET 监测(截定点 39°C)温度探头的患者,消融相关内镜下食管病变的发生率相当低。