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使用分支型腔内移植物进行0区着陆胸主动脉腔内修复术的有效性和微创性

Effectiveness and Minimal-Invasiveness of Zone 0 Landing Thoracic Endovascular Aortic Repair Using Branched Endograft.

作者信息

Kudo Tomoaki, Kuratani Toru, Sawa Yoshiki, Miyagawa Shigeru

机构信息

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita 5650871, Osaka, Japan.

Department of Minimally Invasive Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita 5650871, Osaka, Japan.

出版信息

J Clin Med. 2022 Nov 26;11(23):6981. doi: 10.3390/jcm11236981.

Abstract

Background: Zone 0 landing thoracic endovascular aortic repair (TEVAR) for the treatment of aortic arch diseases has become a topic of interest. This study aimed to verify whether branced TEVAR (bTEVAR) is an effective and a more minimally invasive treatment by comparing the outcomes of bTEVAR and hybrid TEVAR (hTEVAR) in landing zone 0. Methods: This retrospective, single-center, observational cohort study included 54 patients (bTEVAR, n = 25; hTEVAR, n = 29; median age, 78 years; median follow-up period, 5.4 years) from October 2012 to June 2018. The logistic Euro-SCORE was significantly higher in the bTEVAR group than in the hTEVAR group (38% vs. 21%, p < 0.001). Results: There was no significant difference the in-hospital mortality between the bTEVAR and hTEVAR groups (0% vs. 3.4%, p = 1.00). The operative time (220 vs. 279 min, p < 0.001) and length of hospital stay (12 vs. 17 days, p = 0.013) were significantly shorter in the bTEVAR group than in the hTEVAR group. The 7-year free rates of aorta-related deaths (bTEVAR [95.5%] vs. hTEVAR [86.9%], Log-rankp = 0.390) and aortic reintervention (bTEVAR [86.3%] vs. hTEVAR [86.9%], Log-rankp = 0.638) were not significantly different. Conclusions: The early and mid-term outcomes in both groups were satisfactory. bTEVAR might be superior to hTEVAR in that it is less invasive. Therefore, bTEVAR may be considered an effective and a more minimally invasive treatment for high-risk patients.

摘要

背景

0区着陆的胸主动脉腔内修复术(TEVAR)用于治疗主动脉弓疾病已成为一个备受关注的话题。本研究旨在通过比较0区着陆的分支型TEVAR(bTEVAR)和杂交TEVAR(hTEVAR)的治疗结果,验证bTEVAR是否为一种有效且创伤更小的治疗方法。方法:这项回顾性、单中心、观察性队列研究纳入了2012年10月至2018年6月期间的54例患者(bTEVAR组25例;hTEVAR组29例;中位年龄78岁;中位随访期5.4年)。bTEVAR组的逻辑欧洲心脏手术风险评估系统(Euro-SCORE)显著高于hTEVAR组(38%对21%,p<0.001)。结果:bTEVAR组和hTEVAR组的院内死亡率无显著差异(0%对3.4%,p=1.00)。bTEVAR组的手术时间(220对279分钟,p<0.001)和住院时间(12对17天,p=0.013)显著短于hTEVAR组。主动脉相关死亡的7年无事件生存率(bTEVAR组[95.5%]对hTEVAR组[86.9%],对数秩检验p=0.390)和主动脉再次干预率(bTEVAR组[86.3%]对hTEVAR组[86.9%],对数秩检验p=0.638)无显著差异。结论:两组的早期和中期结果均令人满意。bTEVAR在创伤性方面可能优于hTEVAR。因此,对于高危患者,bTEVAR可被视为一种有效且创伤更小的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c92/9738699/0b3691df6343/jcm-11-06981-g001.jpg

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