Kawatou Masahide, Minakata Kenji, Sakamoto Kazuhisa, Nakatsu Taro, Tazaki Junichi, Higami Hirooki, Uehara Kyokun, Yamazaki Kazuhiro, Inoue Kanji, Kimura Takeshi, Sakata Ryuzo
Department of Cardiovascular Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Interact Cardiovasc Thorac Surg. 2017 Aug 1;25(2):246-253. doi: 10.1093/icvts/ivx111.
Although conventional open repair is our preference for patients with aortic arch aneurysms, we have often chosen thoracic endovascular aneurysm repair (TEVAR) with a handmade branched stent graft (bTEVAR) in high-risk patients. The aim of this study was to compare the midterm clinical outcomes of our bTEVAR technique to those of the open repair.
Between January 2007 and December 2014, we treated 129 patients with aortic arch aneurysm by means of either conventional open repair (OPEN, n = 61) or bTEVAR (n = 68) at our institution.
The mean ages were 70.5 ± 12.7 years in the OPEN group and 72.7 ± 12.5 years in the bTEVAR group (P = 0.32). The aetiologies included true aneurysm in 101 patients (78.3%) and chronic dissection in 26 (20.1%). There were 2 (3.3%) in-hospital deaths in the OPEN group and 3 (4.4%) in the bTEVAR group. The mean follow-up duration was 3.0 ± 2.1 years (2.4 ± 1.9 years in the OPEN group and 3.6 ± 2.3 years in the bTEVAR group). There was no difference in 5-year aneurysm-related mortality between groups (10.7% in OPEN vs 12.8% in bTEVAR, P = 0.50). In terms of late additional procedures, however, none were required in the OPEN group, whereas 10 (15.4%) additional endovascular repairs and 4 (6.2%) open repairs were required in the bTEVAR group.
Our bTEVAR could be performed with low early mortality, and it yielded similar midterm aneurysm-related mortality to that of conventional open repair. However, these patients undergoing this technique required more late additional procedures than those undergoing conventional open repair.
尽管传统开放修复术是我们治疗主动脉弓动脉瘤患者的首选方法,但对于高危患者,我们常选择使用手工制作的分支型覆膜支架(bTEVAR)进行胸主动脉腔内修复术(TEVAR)。本研究旨在比较我们的bTEVAR技术与开放修复术的中期临床疗效。
2007年1月至2014年12月期间,我们在本机构采用传统开放修复术(OPEN,n = 61)或bTEVAR(n = 68)治疗了129例主动脉弓动脉瘤患者。
OPEN组的平均年龄为70.5±12.7岁,bTEVAR组为72.7±12.5岁(P = 0.32)。病因包括真性动脉瘤101例(78.3%)和慢性夹层26例(20.1%)。OPEN组有2例(3.3%)住院死亡,bTEVAR组有3例(4.4%)。平均随访时间为3.0±2.1年(OPEN组为2.4±1.9年,bTEVAR组为3.6±2.3年)。两组间5年动脉瘤相关死亡率无差异(OPEN组为10.7%,bTEVAR组为12.8%,P = 0.50)。然而,在后期额外手术方面,OPEN组无需额外手术,而bTEVAR组需要10例(15.4%)额外的腔内修复和4例(6.2%)开放修复。
我们的bTEVAR技术早期死亡率较低,中期动脉瘤相关死亡率与传统开放修复术相似。然而,接受该技术治疗的患者比接受传统开放修复术的患者需要更多的后期额外手术。