Zhang Eva, Christensen Britt, Macrae Finlay Alistair, Leong Rupert
Department of Medicine, Macquarie University, Macquarie Park 2113, Australia.
Department of Gastroenterology, Royal Melbourne Hospital, Melbourne 3050, Australia.
J Clin Med. 2022 Nov 27;11(23):7002. doi: 10.3390/jcm11237002.
The COVID-19 pandemic has caused extended global disruption and changed healthcare behaviour and delivery in patients with inflammatory bowel disease, many of whom take immune modifying treatment. Although there were fears about the vulnerability of IBD patients to SARS-CoV-2 infection, we have learnt that overall IBD patients are equivalent to the general population in both viral acquisition and infection outcomes. Overall IBD patients obtain effective vaccine-induced immune responses, although in some groups an additional vaccine dose is required to constitute a primary course. The pandemic has led to significant changes in healthcare delivery, some of which will be enduring. As we grapple with the challenges of recovery, the lessons learnt will continue to be important in optimising outcomes in future outbreaks.
新冠疫情已造成全球范围的长期混乱,并改变了炎症性肠病患者的医疗行为和医疗服务提供方式,其中许多患者正在接受免疫调节治疗。尽管有人担心炎症性肠病患者易感染新冠病毒,但我们了解到,总体而言,炎症性肠病患者在病毒感染率和感染结果方面与普通人群相当。总体而言,炎症性肠病患者可获得有效的疫苗诱导免疫反应,不过在某些群体中,需要额外接种一剂疫苗才能完成一个基础疗程。疫情导致医疗服务提供方式发生了重大变化,其中一些变化将持续存在。在我们应对恢复过程中的挑战时,所吸取的经验教训对于优化未来疫情中的治疗效果仍将至关重要。