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三明治式(羊膜/结膜-角膜缘自体移植/羊膜)移植术治疗复发性翼状胬肉合并限制性斜视

Sandwich (Amnion/Conjunctival-Limbal Autograft/Amnion) Transplantation for Recurrent Pterygium with Restrictive Strabismus.

作者信息

Wong Hang, Wang Jia-Song, Du Ya-Li, Xie Hua-Tao, Zhang Ming-Chang

机构信息

Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

出版信息

J Clin Med. 2022 Dec 3;11(23):7193. doi: 10.3390/jcm11237193.

DOI:10.3390/jcm11237193
PMID:36498767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9737167/
Abstract

(1) Background: This study aimed to evaluate the clinical outcome of Sandwich (Amnion/Conjunctival-Limbal Autograft/Amnion) transplantation for recurrent pterygium with restrictive strabismus. (2) Methods: This retrospective study included 11 eyes in 11 patients diagnosed with recurrent pterygium with restrictive strabismus who received sandwich transplantation. The outcomes were measured by pterygium recurrence, best-corrected visual acuity, esotropia (prism diopters), and treatment complications. (3) Results: Eleven patients (six males, five females) had a mean age of 60.5 (range 36-80) years. The previously received pterygium excision surgery number was 1.8 ± 1.02 (range 1-4). The mean follow-up period was 19.9 ± 8.41 (range 12-36) months. All patients had a restriction of abduction in the previously operated eye, causing esotropia in the primary position. Pre-operative esotropia was 17.2 (range 10-30) prims diopter (PD). Five eyes (45.5%) had symblepharon before surgery. All patients were orthotropic until the last follow-up. Symblepharon was released in all eyes. Free ocular motility was present in all eyes. No donor site scar formation, scleral melt, or corneal ulcer was noted. (4) Conclusions: Sandwich transplantation for recurrent pterygium with restrictive strabismus is safe and effective.

摘要

(1) 背景:本研究旨在评估三明治式(羊膜/结膜-角膜缘自体移植/羊膜)移植治疗复发性翼状胬肉合并限制性斜视的临床疗效。(2) 方法:本回顾性研究纳入了11例诊断为复发性翼状胬肉合并限制性斜视的患者的11只眼,这些患者接受了三明治式移植。通过翼状胬肉复发情况、最佳矫正视力、内斜视(棱镜度)和治疗并发症来评估疗效。(3) 结果:11例患者(6例男性,5例女性)的平均年龄为60.5岁(范围36 - 80岁)。既往接受翼状胬肉切除手术的次数为1.8 ± 1.02次(范围1 - 4次)。平均随访期为19.9 ± 8.41个月(范围12 - 36个月)。所有患者既往手术眼均有外展受限,导致原在位出现内斜视。术前内斜视度数为17.2(范围10 - 30)棱镜度(PD)。5只眼(45.5%)术前存在睑球粘连。至最后一次随访时所有患者均眼位正。所有眼的睑球粘连均已松解。所有眼均有自由眼球运动。未观察到供体部位瘢痕形成、巩膜溶解或角膜溃疡。(4) 结论:三明治式移植治疗复发性翼状胬肉合并限制性斜视安全有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/4f82bd02b9fd/jcm-11-07193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/dec9fc67564b/jcm-11-07193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/773319f6e7cf/jcm-11-07193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/4f82bd02b9fd/jcm-11-07193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/dec9fc67564b/jcm-11-07193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/773319f6e7cf/jcm-11-07193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58d5/9737167/4f82bd02b9fd/jcm-11-07193-g003.jpg

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本文引用的文献

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Int Med Case Rep J. 2020 May 21;13:201-209. doi: 10.2147/IMCRJ.S245256. eCollection 2020.
2
Identification and Correction of Restrictive Strabismus After Pterygium Excision Surgery.翼状胬肉切除术后限制性斜视的识别与矫正。
Am J Ophthalmol. 2019 Jun;202:6-14. doi: 10.1016/j.ajo.2019.02.004. Epub 2019 Feb 14.
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Recurrent pterygium treatment using mitomycin C, double amniotic membrane transplantation, and a large conjunctival flap.
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Int Med Case Rep J. 2018 Mar 7;11:47-52. doi: 10.2147/IMCRJ.S150969. eCollection 2018.
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Cell Tissue Bank. 2017 Jun;18(2):193-204. doi: 10.1007/s10561-017-9618-5. Epub 2017 Mar 2.
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