铁代谢、铁蛋白和hepcidin 研究的新进展。
New Advances in Iron Metabolism, Ferritin and Hepcidin Research.
机构信息
Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
出版信息
Int J Mol Sci. 2022 Nov 25;23(23):14700. doi: 10.3390/ijms232314700.
Abstract
The interest in the regulation of iron metabolism has increased in recent years with the clarification of the mechanism by which hepcidin regulates systemic iron homeostasis and the discovery of ferritinophagy, the major mechanism of ferritin degradation, which plays a major role in intracellular iron homeostasis and ferroptosis [...].
摘要
近年来，随着铁调素调节全身铁稳态的机制的阐明以及铁蛋白降解的主要机制——铁蛋白噬作用的发现，人们对铁代谢的调节产生了浓厚的兴趣，铁蛋白噬作用在细胞内铁稳态和铁死亡中起着重要作用[... ]。
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