Williamson Casey W, Mayadev Jyoti
Department of Radiation Medicine, Oregon Health & Science University, Portland, OR.
Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA.
Brachytherapy. 2023 Jan-Feb;22(1):15-20. doi: 10.1016/j.brachy.2022.10.004. Epub 2022 Dec 8.
Brachytherapy is a critical component of the definitive management of cervical cancer and allows for the safe delivery of about half of the total effective radiation dose needed for optimal outcomes. Moreover, the dose distribution of brachytherapy is highly conformal, allowing for a therapeutic index currently unmatched by alternative techniques. However, a modern brachytherapy program requires special equipment, infrastructure, and procedural expertise. Unfortunately, multiple lines of evidence suggest that brachytherapy is currently underutilized in the United States. In this review, we examine the importance of brachytherapy, contemporary recommendations, and avenues for growth.
近距离放射治疗是宫颈癌确定性治疗的关键组成部分,能够安全地提供达到最佳治疗效果所需的总有效辐射剂量的大约一半。此外,近距离放射治疗的剂量分布具有高度适形性,这使得其治疗指数目前是其他替代技术无法比拟的。然而,现代近距离放射治疗方案需要特殊的设备、基础设施和操作专业知识。不幸的是,多项证据表明,近距离放射治疗目前在美国未得到充分利用。在本综述中,我们探讨了近距离放射治疗的重要性、当代建议以及发展途径。