Yu Chang, Qiu Jingyue, Xiong Meng, Ou Chen, Zeng Meiyan, Song Houpan
Hunan Provincial Key Laboratory of Diagnostic Research in Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
College of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Front Med (Lausanne). 2022 Nov 23;9:1027534. doi: 10.3389/fmed.2022.1027534. eCollection 2022.
-related gastric ulcer (-related GU) is one of the most common digestive system diseases that have received widespread attention from researchers. The purpose of this article was to analyze the research status and hotspots of -related GU and to predict its future research directions.
The article and review papers associated with -related GU published from 2012 to 2022 were retrieved from the Web of Science Core Collection (WoSCC). The analysis of knowledge maps and bibliometrics was done with CiteSpace 6.1.R2 Basic and VOSviewer 1.6.18.
A total of 2,971 articles were included in the study. Between 2012 and 2022, the number of papers published showed an increasing trend. China was the most prolific country, and the United States was the most influential country. Baylor College of Medicine had the largest number of publications and citations among publishing agencies. published the most articles on the -related GU field, and was the journal with the most cited articles. Yamaoka Y from Japan was the most productive author, and Graham DY from the USA was the most influential author. A keyword and reference analysis showed that the hot topics of research were the mechanism of and the treatment of -related GU. The keywords that emerged in the recent 5 years were oxidative stress, probiotics, competitive acid blocker, vonoprazan, gut microbiota, and neutrophil-activating protein.
Over the recent 10 years, research on -related GU has generally shown an increasing trend. The treatment and pathogenesis of -related GU remain a hot topic of research. The treatment of by oxidative stress and competitive acid inhibitor mechanisms, the influence of gastrointestinal flora on , probiotic adjuvant therapy of -related GU, and the immunoprotective effect of neutrophil activator protein could be popular research directions and trends in the future.
[疾病名称]相关性胃溃疡（[疾病名称]相关GU）是最常见的消化系统疾病之一，受到了研究人员的广泛关注。本文旨在分析[疾病名称]相关GU的研究现状和热点，并预测其未来的研究方向。
从Web of Science核心合集（WoSCC）中检索2012年至2022年发表的与[疾病名称]相关GU的文章和综述论文。使用CiteSpace 6.1.R2 Basic和VOSviewer 1.6.18进行知识图谱和文献计量学分析。
本研究共纳入2971篇文章。2012年至2022年期间，发表的论文数量呈上升趋势。中国是发文量最多的国家，美国是最具影响力的国家。贝勒医学院在出版机构中发表的文章数量和被引次数最多。[某机构]在[疾病名称]相关GU领域发表的文章最多，[某期刊]是被引次数最多的期刊。日本的山冈洋是发文量最多的作者，美国的格雷厄姆·DY是最具影响力的作者。关键词和参考文献分析表明，研究的热点话题是[疾病名称]的机制和[疾病名称]相关GU的治疗。最近5年出现的关键词有氧化应激、益生菌、竞争性酸阻滞剂、沃克拉唑、肠道微生物群和中性粒细胞激活蛋白。
在最近10年里，对[疾病名称]相关GU的研究总体呈上升趋势。[疾病名称]相关GU的治疗和发病机制仍然是研究的热点话题。通过氧化应激和竞争性酸抑制剂机制治疗[疾病名称]、胃肠道菌群对[疾病名称]的影响、[疾病名称]相关GU的益生菌辅助治疗以及中性粒细胞激活蛋白的免疫保护作用可能是未来流行的研究方向和趋势。
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