Department of Chemistry, Research Center for Analytical Sciences, College of Sciences, Northeastern University, Shenyang 110819, China.
CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Chem Commun (Camb). 2023 Jan 3;59(3):314-317. doi: 10.1039/d2cc05650j.
A new strategy using non-porous silica (NPS) spheres as the support and covalent organic frameworks (COFs) as the porous functional shell for liquid chromatography was developed to ensure the independent effect of the COFs on the separation. As a proof of concept, NPS@TPB-DMTP was prepared for liquid chromatographic analysis using 1,3,5-tris(4-aminophenyl)benzene (TPB) and 2,5-dimethoxy-1,4-benzenedicarboxaldehyde (DMTP) as monomers by polymerisation on the surface of NPS. It is a new way of developing COF-based stationary phases, which will be helpful in understanding what effect the COFs will have on separation.
开发了一种使用无孔二氧化硅 (NPS) 球作为载体和共价有机骨架 (COFs) 作为多孔功能壳的新策略，用于液相色谱，以确保 COFs 对分离的独立影响。作为概念验证，使用 1,3,5-三(4-氨基苯基)苯 (TPB) 和 2,5-二甲氧基-1,4-苯二甲醛 (DMTP) 作为单体，通过在 NPS 表面聚合，制备了用于液相色谱分析的 NPS@TPB-DMTP。这是开发基于 COF 的固定相的新方法，有助于理解 COFs 对分离的影响。
