Zhao Ken, Mabud Tarub S, Patel Nihal, Bernstein Mark P, McDermott Meredith, Bryk Hillel, Taslakian Bedros
Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave. H-118H, New York, NY, 10065, USA.
Department of Radiology, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Abdom Radiol (NY). 2023 Mar;48(3):1131-1139. doi: 10.1007/s00261-022-03765-1. Epub 2022 Dec 15.
Non-operative management of hepatic trauma with adjunctive hepatic arterial embolization (HAE) is widely accepted. Despite careful patient selection utilizing CTA, a substantial proportion of angiograms are negative for arterial injury and no HAE is performed. This study aims to determine which CT imaging findings and clinical factors are associated with the presence of active extravasation on subsequent angiography in patients with hepatic trauma.
The charts of 243 adults who presented with abdominal trauma and underwent abdominal CTA followed by conventional angiography were retrospectively reviewed. Of these patients, 49 had hepatic injuries on CTA. Hepatic injuries were graded using the American association for the surgery of trauma (AAST) CT classification, and CT images were assessed for active contrast extravasation, arterial pseudoaneurysm, sentinel clot, hemoperitoneum, laceration in-volving more than 2 segments, and laceration involving specific anatomic landmarks (porta hepatis, hepatic veins, and gallbladder fossa). Medical records were reviewed for pre- and post-angiography blood pressures, hemoglobin levels, and transfusion requirements. Angiographic images and reports were reviewed for hepatic arterial injury and performance of HAE.
In multivariate analysis, AAST hepatic injury grade was significantly associated with increased odds of HAE (Odds ratio: 2.5, 95% CI 1.1, 7.1, p = 0.049). Univariate analyses demonstrated no significant association between CT liver injury grade, CT characteristics of liver injury, or pre-angiographic clinical data with need for HAE.
In patients with hepatic trauma, prediction of need for HAE based on CT findings alone is challenging; such patients require consideration of both clinical factors and imaging findings.
肝外伤的非手术治疗联合肝动脉栓塞术(HAE)已被广泛接受。尽管利用CT血管造影(CTA)仔细选择患者,但仍有相当一部分血管造影显示动脉损伤为阴性,未进行HAE。本研究旨在确定哪些CT影像学表现和临床因素与肝外伤患者后续血管造影中活动性造影剂外渗的存在相关。
回顾性分析243例腹部外伤患者的病历,这些患者均接受了腹部CTA检查,随后进行了传统血管造影。其中,49例患者CTA显示肝损伤。肝损伤采用美国创伤外科学会(AAST)CT分类法进行分级,并评估CT图像上的活动性造影剂外渗、动脉假性动脉瘤、哨兵血块、腹腔积血、累及超过2个肝段的裂伤以及累及特定解剖标志(肝门、肝静脉和胆囊窝)的裂伤。查阅病历以了解血管造影前后的血压、血红蛋白水平和输血需求。回顾血管造影图像和报告以了解肝动脉损伤情况及HAE的实施情况。
多因素分析显示,AAST肝损伤分级与HAE实施几率增加显著相关(比值比:2.5,95%可信区间1.1,7.1,p = 0.049)。单因素分析表明,CT肝损伤分级、肝损伤的CT特征或血管造影前的临床数据与HAE需求之间无显著关联。
对于肝外伤患者,仅根据CT表现预测HAE需求具有挑战性;此类患者需要综合考虑临床因素和影像学表现。