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识别活体供肾移植中可改变的系统层面障碍。

Identifying Modifiable System-Level Barriers to Living Donor Kidney Transplantation.

作者信息

Sandal Shaifali, Schiller Ian, Dendukuri Nandini, Robert Jorane-Tiana, Katergi Khaled, Alam Ahsan, Cantarovich Marcelo, Fiore Julio F, Suri Rita S, Landsberg David, Weber Catherine, Fortin Marie-Chantal

机构信息

Division of Nephrology, Department of Medicine, McGill University Health Centre, Montréal, Québec, Canada.

Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.

出版信息

Kidney Int Rep. 2022 Sep 9;7(11):2410-2420. doi: 10.1016/j.ekir.2022.08.028. eCollection 2022 Nov.

Abstract

INTRODUCTION

Studying existing health systems with variable living donor kidney transplantation (LDKT) performance and understanding factors that drive these differences can inform comprehensive system-level approaches to improve LDKT. We aimed to quantify previously identified barriers and estimate their association with LDKT performance.

METHODS

We conducted a cross-sectional survey of health professionals (HPs). Statements, rated on a Likert scale of "strongly disagree" to "strongly agree", captured themes related to communication; role perception; HP's education, training and comfort; attitudes; referral process; patient; as well as resources and infrastructure. The percentage who agreed with these statements was analyzed and compared by LDKT performance (living donation rates higher or lower than the national average) and participant characteristics.

RESULTS

We obtained 353 complete responses. Themes related to poor communication, poor role perception, and HPs education or training or comfort emerged as barriers to LDKT. When compared with HPs from high-performing provinces, those from low-performing provinces had lower odds of agreeing that their province promoted LDKT (adjusted odd ratio [aOR] = 0.27, 95% confidence interval [CI]: 0.16-0.48). They also had lower odds of initiating discussions about LDKT (aOR = 0.30, 95% CI: 0.17-0.55), and higher odds of agreeing that the transplant team is best suited to discuss LDKT (aOR = 2.64, 95% CI: 1.60-4.33) and that more resources would increase LDKT discussions (aOR = 2.06, 95% CI: 1.25-3.40). Nonphysician role and less than 10 years of experience were associated with the level of agreement across several themes. Creating guidelines, streamlining evaluations, and improving communication were ranked as priorities to increase LDKT.

CONCLUSION

There are system-level barriers to LDKT and some were more prevalent in low-performing provinces. Interventions to eliminate them should be implemented in conjunction with patient-level interventions as part of a comprehensive system-level approach to increase LDKT.

摘要

引言

研究活体供肾移植(LDKT)表现各异的现有卫生系统,并了解导致这些差异的因素,可为改善LDKT的综合系统层面方法提供依据。我们旨在量化先前确定的障碍,并估计它们与LDKT表现之间的关联。

方法

我们对卫生专业人员(HP)进行了一项横断面调查。陈述采用从“强烈不同意”到“强烈同意”的李克特量表评分,涵盖了与沟通、角色认知、HP的教育、培训和舒适度、态度、转诊过程、患者以及资源和基础设施相关的主题。分析并比较了同意这些陈述的百分比与LDKT表现(活体捐赠率高于或低于全国平均水平)及参与者特征之间的关系。

结果

我们获得了353份完整回复。与沟通不畅、角色认知差以及HP的教育、培训或舒适度相关的主题成为LDKT的障碍。与来自高表现省份的HP相比,来自低表现省份的HP同意其所在省份促进LDKT的几率较低(调整后的优势比[aOR]=0.27,95%置信区间[CI]:0.16 - 0.48)。他们发起关于LDKT讨论的几率也较低(aOR = 0.30,95% CI:0.17 - 0.55),而同意移植团队最适合讨论LDKT的几率较高(aOR = 2.64,95% CI:1.60 - 4.33),且同意更多资源会增加LDKT讨论的几率较高(aOR = 2.06,95% CI:1.25 - 3.40)。非医生角色以及工作经验少于10年与多个主题的同意程度相关。制定指南、简化评估和改善沟通被列为增加LDKT的优先事项。

结论

LDKT存在系统层面的障碍,其中一些在低表现省份更为普遍。应将消除这些障碍的干预措施与患者层面的干预措施结合实施,作为增加LDKT的综合系统层面方法的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8507/9751709/d360642b8a26/fx1.jpg

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