人胎盘胰岛素样生长因子II mRNA表达的一个新的5'非编码区。
A new 5'-non-coding region for human placental insulin-like growth factor II mRNA expression.
作者信息
Le Bouc Y, Noguiez P, Sondermeijer P, Dreyer D, Girard F, Binoux M
机构信息
INSERM U 142, Hôpital Trousseau, Paris, France.
出版信息
FEBS Lett. 1987 Sep 28;222(1):181-5. doi: 10.1016/0014-5793(87)80216-8.
PMID:3653397
Abstract
A human placenta cDNA library was screened for insulin-like growth factor II (IGF-II). Four clones were selected, which exhibited an IGF-II cDNA coding sequence identical to those previously described for human adult liver IGF-II cDNA. Extensive sequence diversity was observed in the 5'-non-coding region, probably resulting from differential intron splicing.
摘要
用人胎盘cDNA文库筛选胰岛素样生长因子II（IGF-II）。挑选出四个克隆，它们表现出的IGF-II cDNA编码序列与先前描述的成人肝脏IGF-II cDNA相同。在5'-非编码区观察到广泛的序列多样性，这可能是由于内含子剪接差异所致。
Zotero 插件