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印度北部一家口服替代疗法中心就诊的注射吸毒者皮肤病变的临床流行病学特征:一项横断面研究。

Clinico-epidemiological Aspects of Cutaneous Lesions in Injecting Drug Users Visiting an Oral Substitution Therapy Centre in Northern India: A Cross-Sectional study.

作者信息

Dhillon Shaminder Singh, Kaur Tejinder, Bala Neeru

机构信息

Department of Skin & VD, Government Medical College, Amritsar, Punjab, India.

出版信息

Dermatol Pract Concept. 2022 Oct 1;12(4):e2022154. doi: 10.5826/dpc.1204a154. eCollection 2022 Nov.

Abstract

INTRODUCTION

Drug abuse has been taking a great toll on the health and well-being of the community for the past few decades. Substance abuse can lead to several cutaneous manifestations as direct injuries by the offending drug or the practices of drug usage cause secondary damage to the skin. The early recognition of these signs is of utmost importance to prevent long-term complications.

OBJECTIVES

To study the clinical-epidemiological profile of the skin diseases in Injecting Drug Users (IDU) attending an Oral Substitution Therapy (OST) Center in Northern India and to assess the psychological impact of skin conditions in IDUs attending OSTs.

METHODS

This cross-sectional observational study involved 100 IDUs enrolled from the OST center who were subjected to brief history taking and clinical and dermoscopic evaluation of skin lesions. Dermatological quality of life index (DLQI), Depression, Anxiety, Stress Scale (DASS), and WHO-quality of life (QoL) questionnaire were used to evaluate the impact of skin lesions on psycho-social health and QoL of IDUs.

RESULTS

Cutaneous lesions ranged from track marks to severe ulcerations and scarring. Mucosal lesions also took a toll on several patients. The patients had varying degrees of anxiety, depression, and mental stress.

CONCLUSIONS

Injecting Drug Abusers are prone to acquire skin diseases due to injury caused by drugs as well as by drug practices adopted and the degree of neglect may worsen these conditions. These cutaneous lesions hamper QoL and cause psychosocial disturbances.

摘要

引言

在过去几十年里,药物滥用给社区的健康和福祉造成了巨大损失。药物滥用可导致多种皮肤表现,这是由有害药物直接造成的损伤,或是用药行为对皮肤造成的继发性损害。尽早识别这些症状对于预防长期并发症至关重要。

目的

研究在印度北部一家口服替代疗法(OST)中心接受治疗的注射吸毒者(IDU)皮肤疾病的临床流行病学特征,并评估皮肤状况对接受OST治疗的IDU的心理影响。

方法

这项横断面观察性研究纳入了100名来自OST中心的IDU,对他们进行了简要病史采集以及皮肤病变的临床和皮肤镜评估。使用皮肤病生活质量指数(DLQI)、抑郁、焦虑、压力量表(DASS)和世界卫生组织生活质量(QoL)问卷来评估皮肤病变对IDU心理社会健康和生活质量的影响。

结果

皮肤病变范围从针眼痕迹到严重溃疡和瘢痕形成。黏膜病变也对多名患者造成了影响。患者存在不同程度的焦虑、抑郁和精神压力。

结论

注射吸毒者由于药物造成的损伤以及所采用的吸毒行为而容易患上皮肤病,而忽视程度可能会使这些情况恶化。这些皮肤病变会妨碍生活质量并导致心理社会障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34f5/9681189/1d331b131b44/dp1204a154g001.jpg

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