Department of Surgery, The University of Auckland, Auckland, New Zealand.
Alimetry, Auckland, New Zealand.
Am J Gastroenterol. 2023 Jun 1;118(6):1047-1057. doi: 10.14309/ajg.0000000000002077. Epub 2022 Dec 20.
Body surface gastric mapping (BSGM) is a new noninvasive test of gastric function. BSGM offers several novel and improved biomarkers of gastric function capable of differentiating patients with overlapping symptom profiles. The aim of this study was to define normative reference intervals for BSGM spectral metrics in a population of healthy controls.
BSGM was performed in healthy controls using Gastric Alimetry (Alimetry, New Zealand) comprising a stretchable high-resolution array (8 × 8 electrodes; 196 cm 2 ), wearable Reader, and validated symptom-logging App. The evaluation encompassed a fasting baseline (30 minutes), 482 kCal meal, and 4-hour postprandial recording. Normative reference intervals were calculated for BSGM metrics including the Principal Gastric Frequency, Gastric Alimetry Rhythm Index (a measure of the concentration of power in the gastric frequency band over time), body mass index (BMI)-adjusted amplitude (μV), and fed:fasted amplitude ratio. Data were reported as median and reference interval (5th and/or 95th percentiles).
A total of 110 subjects (55% female, median age 32 years [interquartile range 24-50], median BMI 23.8 kg/m 2 [interquartile range 21.4-26.9]) were included. The median Principal Gastric Frequency was 3.04 cycles per minute; reference interval: 2.65-3.35 cycles per minute. The median Gastric Alimetry Rhythm Index was 0.50; reference interval: ≥0.25. The median BMI-adjusted amplitude was 37.6 μV; reference interval: 20-70 μV. The median fed:fasted amplitude ratio was 1.85; reference interval ≥1.08. A higher BMI was associated with a shorter meal-response duration ( P = 0.014).
This study provides normative reference intervals for BSGM spectral data to inform diagnostic interpretations of abnormal gastric function.
体表胃映射（BSGM）是一种新的非侵入性胃功能测试。BSGM 提供了几种新的和改进的胃功能生物标志物，能够区分具有重叠症状谱的患者。本研究的目的是在健康对照组中定义 BSGM 光谱指标的正常参考区间。
使用 Gastric Alimetry（Alimetry，新西兰）在健康对照组中进行 BSGM，该仪器包括可拉伸的高分辨率阵列（8×8 电极；196 cm 2 ）、可穿戴式阅读器和经过验证的症状记录应用程序。评估包括空腹基线（30 分钟）、482 kCal 餐和餐后 4 小时记录。计算了 BSGM 指标的正常参考区间，包括主要胃频率、胃测仪节律指数（衡量一段时间内胃频带功率浓度的指标）、体重指数（BMI）调整后的振幅（μV）和进食：空腹振幅比。数据以中位数和参考区间（第 5 百分位和/或第 95 百分位）报告。
共纳入 110 名受试者（55%为女性，中位年龄 32 岁[四分位间距 24-50]，中位 BMI 23.8 kg/m 2 [四分位间距 21.4-26.9]）。主要胃频率的中位数为 3.04 次/分钟；参考区间：2.65-3.35 次/分钟。胃测仪节律指数的中位数为 0.50；参考区间：≥0.25。BMI 调整后的振幅中位数为 37.6 μV；参考区间：20-70 μV。进食：空腹振幅比的中位数为 1.85；参考区间≥1.08。较高的 BMI 与较短的餐时反应持续时间相关（P=0.014）。
本研究提供了 BSGM 光谱数据的正常参考区间，为异常胃功能的诊断解释提供了依据。
