Weinstock L B, Kothari T, Sharma R N, Rosenfeld S I
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri.
Gastroenterology. 1987 Nov;93(5):1116-8. doi: 10.1016/0016-5085(87)90576-2.
This paper describes a previously unreported finding of abdominal pain as the only lifelong manifestation of hereditary angioedema in multiple family members. This diagnosis was obscured by the absence of cutaneous, oropharyngeal, and respiratory involvement. Barium studies performed during painful attacks showed transient intestinal wall edema which, along with abnormalities in the C4 level and C1 esterase inhibitor activity, confirmed the diagnosis. It is important that hereditary angioedema be recognized in its various forms so that invasive procedures can be avoided and prophylactic therapy can be administered.
腹痛是多个家庭成员遗传性血管性水肿唯一的终生表现。由于没有皮肤、口咽和呼吸道受累，该诊断变得模糊不清。在疼痛发作期间进行的钡剂检查显示肠道壁有短暂水肿，这与C4水平和C1酯酶抑制剂活性异常一起证实了诊断。重要的是要认识到遗传性血管性水肿的各种形式，以便避免侵入性操作并进行预防性治疗。
