Fazal Kamran, Fazal Adnan, Siddiqui Irfan, Mumtaz Hassan, Basir Abdul, Butt Muhammad Meezan, Aman Muhammad, Khan Faheemullah, Ahmad Izaz, Shams Yumna, Bashir Anam
Department of Radiology, Aga Khan University Hospital, Pakistan.
Department of Cardiology, National Institute of Cardiovascular Diseases, Pakistan.
Ann Med Surg (Lond). 2022 Nov 18;84:104938. doi: 10.1016/j.amsu.2022.104938. eCollection 2022 Dec.
Testicular carcinoma is the most common cancer among males aged 15-34 years. The known risk factors for testicular cancer include undescended testis (cryptorchidism), testicular dysfunction, perinatal factors and prior history of cancer in one testis. We aimed to determine the diagnostic accuracy of color doppler ultrasound in diagnosis of testicular carcinoma using histopathology as GOLD STANDARD.
ology: A cross sectional study was conducted from July 2015 to Feb 2016 at the Department of Radiology, Jinnah Post Graduate Medical Center, Karachi. 311 subjects were selected through inpatient/outpatient or emergency department. Patients were evaluated for testicular carcinoma by color doppler ultrasound on Toshiba nemio. Finding of color doppler ultrasound was compared with histopathology. True positive, true negative, false positive, false negative as per operational definition was determined.
Mean age of the patients of the study was 41.76 ± 8.11 (30-50) and mean and SD of Duration of symptoms was 5.5 ± 3.5 (4-15) months. Of 175(56.27%) subjects diagnosed as testicular carcinoma on CDUS, only 160(48.55%) were subsequently found to have testicular carcinoma. sensitivity of CDUS in diagnosing scrotal diseases was 88.8% while specificity was 78.1%.
We conclude that CDUS is an excellent, safe, and reliable method for evaluating patients with testicular carcinoma. It helps to improve patient's management, especially by preventing unnecessary surgical exploration. It is also convenient and easy to perform. But it has its own limitations, and requires adequate expertise and experience. Its results are also equipment dependent.
睾丸癌是15至34岁男性中最常见的癌症。睾丸癌的已知风险因素包括隐睾（睾丸未降）、睾丸功能障碍、围产期因素以及一侧睾丸既往癌症病史。我们旨在以组织病理学作为金标准，确定彩色多普勒超声诊断睾丸癌的诊断准确性。
2015年7月至2016年2月在卡拉奇真纳研究生医学中心放射科进行了一项横断面研究。通过住院/门诊或急诊科选取311名受试者。在东芝Nemio上用彩色多普勒超声对患者进行睾丸癌评估。将彩色多普勒超声的检查结果与组织病理学结果进行比较。根据操作定义确定真阳性、真阴性、假阳性、假阴性。
研究患者的平均年龄为41.76±8.11（30 - 50）岁，症状持续时间的平均值和标准差为5.5±3.5（4 - 15）个月。在经彩色多普勒超声诊断为睾丸癌的175名（56.27%）受试者中，随后仅发现160名（48.55%）患有睾丸癌。彩色多普勒超声诊断阴囊疾病的敏感性为88.8%，特异性为78.1%。
我们得出结论，彩色多普勒超声是评估睾丸癌患者的一种优秀、安全且可靠的方法。它有助于改善患者的管理，特别是通过避免不必要的手术探查。它也方便易行。但它有自身的局限性，需要足够的专业知识和经验。其结果也依赖于设备。
