Gebresilasie Shimelis Fantu, Zegeye Andualem
Department of Obstetrics & Gynecology, College of Medicine & Health Sciences, Hawassa University, Ethiopia.
Ann Med Surg (Lond). 2022 Nov 17;84:104873. doi: 10.1016/j.amsu.2022.104873. eCollection 2022 Dec.
Cervical cancer is the commonest pelvic malignancy in the world, forth among women cancers, but 2nd commonest after breast cancer in the low & middle income countries. The disease is the second common in Ethiopia, with a prevalence of 13.4% with similar impact of cancer death. The aim of this study is to know the degree of cervical cancer among the suspected, & its associated factors among the women visiting the hospital for cervical cancer & precancer screening at specific period.
A five years retrospective hospital based cross sectional study was conducted. All clients who came for screening with a visual inspection using acetic acid (VIA) & suspicious of cancer were included. Finally, every suspected woman with a complete chart was included. Data was coded and entered using Epi Data Version 3.1 then was exported to SPSS version 21 for analysis. Proportion, mean and standard deviation were used to describe the study variables. Then bivariate and multivariate logistic regression analyses were used to identify association between independent & outcome variables. Adjusted Odds Ratio (AOR) with 95% Confidence interval (CI) and p value (<0.05) were computed to assess the presence and degree of statistical association between dependent and independent variables.
The prevalence of cervical cancer among the study women was 28%. Illiterate women suspicious with cervical cancer after positive test have five times increased odds of being diagnosed with cervical cancer than those who had formal education AOR 4.885(0.180, 0.741) 95%CI. Women with multiple sexual partners had eleven times increased odds of having cervical cancer than those with single sexual partner AOR 11.5 (1.273,24.34) 95%CI. Also, women who had referral for suspicious lesion for cervical cancer had significant association AOR 5.477(1.715-17.498) 95% CI.
This study has revealed a significant proportion of cervical cancer among the participants; and the factors associated with cervical cancer were multiple sexual partners, poor educational status (Illiterate), & those referred for suspected disease.
宫颈癌是全球最常见的盆腔恶性肿瘤,在女性癌症中排名第四,但在低收入和中等收入国家中仅次于乳腺癌,是第二常见的癌症。该疾病在埃塞俄比亚排第二位,患病率为13.4%,对癌症死亡的影响类似。本研究的目的是了解特定时期到医院进行宫颈癌及癌前筛查的女性中,疑似宫颈癌的程度及其相关因素。
进行了一项基于医院的五年回顾性横断面研究。纳入所有前来进行醋酸目视检查(VIA)且疑似癌症的筛查患者。最后,纳入每一位病历完整的疑似女性。数据使用Epi Data 3.1版本进行编码和录入,然后导出到SPSS 21版本进行分析。使用比例、均值和标准差来描述研究变量。然后采用双变量和多变量逻辑回归分析来确定自变量与结果变量之间的关联。计算调整后的优势比(AOR)及95%置信区间(CI)和p值(<0.05),以评估因变量和自变量之间统计关联的存在及程度。
研究女性中宫颈癌的患病率为28%。检测呈阳性后疑似宫颈癌的文盲女性被诊断为宫颈癌的几率比受过正规教育的女性高五倍,调整后的优势比为4.885(0.180,0.741),95%置信区间。有多个性伴侣的女性患宫颈癌的几率比只有一个性伴侣的女性高十倍,调整后的优势比为11.5(1.273,24.34),95%置信区间。此外,因宫颈癌可疑病变而被转诊的女性存在显著关联,调整后的优势比为5.477(1.715 - 17.498),95%置信区间。
本研究揭示了参与者中相当比例的宫颈癌;与宫颈癌相关的因素包括多个性伴侣、教育程度低(文盲)以及因疑似疾病而被转诊的人。