Faculty of Medicine, Department of Radiation Oncology, Akdeniz University, Antalya, Turkey.
Technol Cancer Res Treat. 2022 Jan-Dec;21:15330338221143937. doi: 10.1177/15330338221143937.
The development of new techniques in radiotherapy (RT) provides a better planned target volume (PTV) dose distribution while further improving the protection of organs at risk (OARs). The study aims to present the dosimetric results of studies using hybrid techniques in whole-breast radiotherapy (WBRT). This systematic literature review was conducted by scanning the relevant literature in PubMed, Scopus, and Web of Science following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Among the parameters are dose values for PTV and OARs beam contribute ratios, the value of monitors, and treatment times for different RT techniques. Initially, 586 articles were identified; 196 duplicate articles were removed leaving 391 articles for screening. Three-hundred and thirty-seven irrelevant articles were excluded, leaving 54 studies assessed for eligibility. A total of 22 articles met the search criteria to evaluate dosimetric results of hybrid and other RT techniques in WBRT. According to the dosimetric data of the studies, hybrid intensity-modulated RT (H-IMRT) and hybrid volumetric-modulated arc therapy (H-VMAT) techniques give dosimetrically advantageous results in WBRT compared to other RT techniques. Hybrid techniques using appropriate beams contribute value and show great promise in improving dosimetric results in WBRT. However, there is a need for new studies showing the long-term clinical results of hybrid RT.
放疗（RT）新技术的发展提供了更好的计划靶区（PTV）剂量分布，同时进一步提高了对危及器官（OARs）的保护。本研究旨在介绍使用混合技术进行全乳放疗（WBRT）的研究的剂量学结果。 这项系统文献回顾通过扫描 PubMed、Scopus 和 Web of Science 中的相关文献进行，遵循系统评价和荟萃分析的首选报告项目（PRISMA）指南。参数包括 PTV 和 OARs 的剂量值、射束贡献比、监视器值以及不同 RT 技术的治疗时间。最初，确定了 586 篇文章；排除 196 篇重复文章，留下 391 篇文章进行筛选。排除 337 篇不相关的文章，留下 54 篇符合条件的研究进行评估。共有 22 篇文章符合搜索标准，用于评估 WBRT 中混合和其他 RT 技术的剂量学结果。 根据研究的剂量学数据，与其他 RT 技术相比，混合强度调制 RT（H-IMRT）和混合容积调制弧治疗（H-VMAT）技术在 WBRT 中提供了具有优势的剂量学结果。 使用适当射束的混合技术具有贡献价值，并在改善 WBRT 中的剂量学结果方面显示出巨大的潜力。然而，需要新的研究来展示混合 RT 的长期临床结果。
