Cardoso Michael, Sidhom Mark, Udovitch Mark, Young Tony, Arumugam Sankar
Liverpool and Macarthur Cancer Therapy Centres and Ingham Institute, Sydney, New South Wales, Australia.
South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
J Med Imaging Radiat Oncol. 2023 Feb;67(1):111-118. doi: 10.1111/1754-9485.13499. Epub 2022 Dec 20.
To evaluate the feasibility of prostate intrafraction motion monitoring using the SeedTracker real-time image guidance system in order to improve targeting accuracy in prostate radiotherapy.
SeedTracker was used to monitor prostate gold fiducial seeds with kV x-ray imaging during radiotherapy in 30 patients. Feedback from radiation therapists was collected via the use of a user evaluation form. The impact on treatment time was established by using a record and verify system. The effective dose and a risk of exposure-induced cancer death (REID) were estimated for a 60-year-old patient when using the SeedTracker system.
A total of 22 radiation therapists completed user evaluation forms. The time taken to prepare a reference data set for one patient varied with three (13.6%) radiation therapists taking less than 2 min, 10 (45.5%) between 2 and 4 min, eight (36.4%) between 4 and 6 min and one (4.5%) between 6 and 8 min. The useability of the SeedTracker system was reported as 'easy' by 21 (95.5%) radiation therapists and 'hard' by 1 (4.5%) radiation therapist. Mean treatment time changed from 6 to 7 min with prostate-only radiotherapy treatment and from 6.9 to 10.2 min with prostate and whole pelvis radiotherapy treatments. The maximum effective dose with the SeedTracker was 1.6276 mSv, and increase in REID was 0.007%.
The SeedTracker real-time image guidance system is a feasible tool to use in radiotherapy departments to monitor and correct for prostate intrafraction motion.
评估使用SeedTracker实时图像引导系统监测前列腺分次内运动的可行性,以提高前列腺放疗的靶向准确性。
在30例患者的放疗过程中,使用SeedTracker通过千伏X线成像监测前列腺金标籽源。通过使用用户评估表收集放射治疗师的反馈。使用记录与验证系统确定对治疗时间的影响。估算了一名60岁患者使用SeedTracker系统时的有效剂量和暴露诱发癌症死亡风险(REID)。
共有22名放射治疗师填写了用户评估表。为一名患者准备参考数据集所需的时间各不相同,3名(13.6%)放射治疗师用时不到2分钟,10名(45.5%)用时在2至4分钟之间,8名(36.4%)用时在4至6分钟之间,1名(4.5%)用时在6至8分钟之间。21名(95.5%)放射治疗师认为SeedTracker系统“易于使用”,1名(4.5%)放射治疗师认为“难以使用”。单纯前列腺放疗时平均治疗时间从6分钟变为7分钟,前列腺和全盆腔放疗时从6.9分钟变为10.2分钟。使用SeedTracker时的最大有效剂量为1.6276 mSv,REID增加了0.007%。
SeedTracker实时图像引导系统是放疗科室用于监测和校正前列腺分次内运动的可行工具。