Matsumoto Naoya, Sugai Shonosuke, Suzuki Yasuyuki, Iguchi Nobuo, Nanasato Mamoru, Kiso Keisuke, Taniguchi Yasuyo, Yoneyama Tatsuya, Okuda Koichi, Nakajima Kenichi
Department of Cardiology, Nihon University Hospital, Tokyo, Japan.
Department of Cardiology, Sakakibara Heart Institute, Fuchu, Japan.
Ann Nucl Cardiol. 2022;8(1):36-41. doi: 10.17996/anc.22-00163. Epub 2022 Aug 31.
: A working group (WG) of the Japanese Society of Nuclear Cardiology (JSNC) determined Japanese normal databases of myocardial perfusion single-photon emission computed tomography (SPECT) on semi-conductor gamma camera (D-SPECT), and the aim of this study was to validate its clinical utility. : The normal myocardial perfusion SPECT (MPS) databases of Japanese patients in the Tl stress/redistribution protocol (Tl protocol), Tc stress/rest or rest/stress protocol (Tc protocol), and rest Tc/stress Tl simultaneous acquisition dual-isotope protocol (SDI protocol) were created by JSNC WG. The WG collected clinical cases for the Tl protocol (male/female [m/f], 8/8), Tc protocol (m/f, 9/7), and SDI protocol (m/f, 10/10) from WG participating hospitals. Four WG members read those clinical cases on a 17-segment and 5-point scale (0-4). Using the most frequent values as the score for each segment, weighted κ values were calculated with the scores obtained from quantitative perfusion software (QPS). : Weighted κ values were as follows; Tl stress/female, 0.77; Tl rest/female, 0.74; Tl stress/male, 0.81; Tl rest/male, 0.68; Tc stress/female, 0.77; Tc rest/female, 0.62; Tc stress/male, 0.77; Tc rest/male, 0.75; SDI stress/female, 0.87; SDI rest/female, 0.82; SDI stress/male, 0.87; SDI rest/male, 0.85. : The diagnostic accuracy of Japanese MPS normal databases on D-SPECT were comparable with nuclear cardiology expert reading and further clinical applications are expected.
日本核心脏病学会（JSNC）的一个工作组确定了基于半导体伽马相机（D-SPECT）的心肌灌注单光子发射计算机断层扫描（SPECT）的日本正常数据库，本研究的目的是验证其临床实用性。日本核心脏病学会工作组创建了铊负荷/再分布方案（铊方案）、锝负荷/静息或静息/负荷方案（锝方案）以及静息锝/负荷铊同步采集双同位素方案（SDI方案）下日本患者的正常心肌灌注SPECT（MPS）数据库。该工作组从参与工作组的医院收集了铊方案（男/女[m/f]，8/8）、锝方案（m/f，9/7）和SDI方案（m/f，10/10）的临床病例。四名工作组成员按照17节段和5分制（0-4）阅读这些临床病例。将最常见的值作为每个节段的分数，使用从定量灌注软件（QPS）获得的分数计算加权κ值。加权κ值如下：铊负荷/女性，0.77；铊静息/女性，0.74；铊负荷/男性，0.81；铊静息/男性，0.68；锝负荷/女性，0.77；锝静息/女性，0.62；锝负荷/男性，0.77；锝静息/男性，0.75；SDI负荷/女性，0.87；SDI静息/女性，0.82；SDI负荷/男性，0.87；SDI静息/男性，0.85。基于D-SPECT的日本MPS正常数据库的诊断准确性与核心脏病学专家阅读相当，预计会有进一步的临床应用。
