Sandyk R, Bernick C, Lee S M, Stern L Z, Iacono R P, Bamford C R
Department of Neurology, University of Arizona Health Sciences Center, Tucson.
Int J Neurosci. 1987 Aug;35(3-4):233-5. doi: 10.3109/00207458708987132.
Restless legs syndrome (RLS) is a poorly understood, often distressing condition that is particularly prevalent among patients with chronic renal failure. A wide variety of medications have been used to treat RLS with variable results. In order to evaluate the efficacy of carbidopa/levodopa therapy, eight consecutive uremic patients with RLS on maintenance hemodialysis were treated with doses ranging from 25/100 to 25/250 twice daily. Six of eight patients obtained satisfactory relief which has continued for 3 months follow-up. Carbidopa-levodopa appears to be an effective opinion in management of RLS in patients with chronic rental failure.
不宁腿综合征（RLS）是一种了解甚少、常令人痛苦的病症，在慢性肾衰竭患者中尤为普遍。已使用多种药物治疗RLS，但效果各异。为评估卡比多巴/左旋多巴疗法的疗效，对8例维持性血液透析的尿毒症RLS患者连续给予每日2次、剂量范围为25/100至25/250的治疗。8例患者中有6例获得了满意的缓解，且在3个月的随访期内持续有效。卡比多巴-左旋多巴似乎是治疗慢性肾衰竭患者RLS的一种有效药物。
