Suppr超能文献

咖啡和绿茶的摄入与高血压人群和非高血压人群的心血管疾病死亡率。

Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension.

机构信息

Department of Social Medicine Osaka University Graduate School of Medicine Osaka Japan.

Institute for Global Health Policy Research, Bureau of International Health Cooperation National Center for Global Health and Medicine Tokyo Japan.

出版信息

J Am Heart Assoc. 2023 Jan 17;12(2):e026477. doi: 10.1161/JAHA.122.026477. Epub 2022 Dec 21.

Abstract

Background This study was conducted to examine the impacts of coffee and green tea consumption on cardiovascular disease (CVD) mortality among people with severe hypertension. Methods and Results In the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk), 18 609 participants (6574 men and 12 035 women) aged 40 to 79 years at baseline who completed a lifestyle, diet, and medical history questionnaire, and health examinations, were followed up until 2009. We classified the participants into four blood pressure (BP) categories: optimal and normal BP, high-normal BP, grade 1 hypertension, and grade 2-3 hypertension. A Cox proportional hazard model was used to calculate the multivariable hazard ratios with 95% CIs of CVD mortality. During the 18.9 years of median follow-up, a total of 842 CVD deaths were documented. Coffee consumption was associated with an increased risk of CVD mortality among people with grade 2-3 hypertension; the multivariable hazard ratios (95% CI) of CVD mortality were 0.98 (0.67-1.43) for <1 cup/day, 0.74 (0.37-1.46) for 1 cup/day, and 2.05 (1.17-3.59) for ≥2 cups/day, compared with non-coffee drinkers. Such associations were not found among people with optimal and normal, high-normal BP, and grade 1 hypertension. Green tea consumption was not associated with an increased risk of CVD across any BP categories. Conclusions Heavy coffee consumption was associated with an increased risk of CVD mortality among people with severe hypertension, but not people without hypertension and with grade 1 hypertension. In contrast, green tea consumption was not associated with an increased risk of CVD mortality across all categories of BP.

摘要

背景 本研究旨在探讨咖啡和绿茶的摄入对重度高血压患者心血管疾病(CVD)死亡率的影响。

方法和结果 在日本癌症风险合作队列研究(JACC)中,共有 18609 名年龄在 40 至 79 岁的参与者(男性 6574 名,女性 12035 名)在基线时完成了生活方式、饮食和病史问卷以及健康检查,随访至 2009 年。我们将参与者分为四个血压(BP)类别:最佳和正常 BP、高正常 BP、1 级高血压和 2-3 级高血压。使用 Cox 比例风险模型计算多变量风险比及其 95%置信区间(CI)的 CVD 死亡率。在中位随访 18.9 年期间,共记录了 842 例 CVD 死亡。咖啡的摄入与 2-3 级高血压患者的 CVD 死亡率风险增加相关;CVD 死亡率的多变量风险比(95%CI)为<1 杯/天的 0.98(0.67-1.43)、1 杯/天的 0.74(0.37-1.46)和≥2 杯/天的 2.05(1.17-3.59),与非咖啡饮用者相比。在最佳和正常、高正常 BP 和 1 级高血压的人群中未发现此类关联。绿茶的摄入与任何 BP 类别均不增加 CVD 的风险相关。

结论 重度高血压患者大量摄入咖啡与 CVD 死亡率的增加相关,但不包括无高血压和 1 级高血压患者。相反,绿茶的摄入与所有 BP 类别均不增加 CVD 死亡率的风险相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c918/9939061/b92e05f58d70/JAH3-12-e026477-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验