Chen Jilei, Fu Wenrong, Jiang Feng-Lei, Liu Yi, Jiang Peng
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Ministry of Education), College of Chemistry and Molecular Sciences & School of Pharmaceutical Sciences, Wuhan University, Wuhan 430072, P. R. China.
State Key Laboratory of Separation Membranes and Membrane Process, School of Chemistry, Tiangong University, Tianjin 300387, P. R. China.
J Mater Chem B. 2023 Jan 25;11(4):702-715. doi: 10.1039/d2tb01503j.
As a new two-dimensional (2D) material, transition metal carbides and nitrides (MXenes) have attracted much attention because of their excellent physical and chemical properties. In recent years, MXenes have been widely applied in the biological field due to their high biocompatibility, abundant surface groups, good conductivity, and photothermal properties. Here, the main synthesis methods of MXenes and the analysis of the advantages and disadvantages of each method are presented in detail. Then, the latest developments of MXenes in the biological field, including biosensing, antibacterial activity, reactive oxygen species (ROS) and free radical scavenging, tissue repair and antitumor therapy are comprehensively reviewed. Finally, the current challenges and future development trends of MXenes in biological applications are discussed.
作为一种新型二维（2D）材料，过渡金属碳化物和氮化物（MXenes）因其优异的物理和化学性质而备受关注。近年来，MXenes因其高生物相容性、丰富的表面基团、良好的导电性和光热性质而被广泛应用于生物领域。在此，详细介绍了MXenes的主要合成方法，并分析了每种方法的优缺点。然后，全面综述了MXenes在生物领域的最新进展，包括生物传感、抗菌活性、活性氧（ROS）和自由基清除、组织修复和抗肿瘤治疗。最后，讨论了MXenes在生物应用中的当前挑战和未来发展趋势。
