丙戊酸盐所致高氨血症性脑病
Valproate Induced Hyperammonemic Encephalopathy.
作者信息
Qayyum Wajeeha, Yousafzai Zaland Ahmed, Iqbal Muhammad Shahid, Khan Sohail, Amin Qazi Kamran, Shafiqs Ihtesham
机构信息
Department of Medicine.
Department of Neurology, Rehman Medical Institute, Peshawar, Pakistan.
出版信息
J Ayub Med Coll Abbottabad. 2022 Oct-Dec;34(Suppl 1)(4):S1038-S1039. doi: 10.55519/JAMC-04-S4-10190.
Valproate is a commonly prescribed anticonvulsant drug. It has a potential to cause hyperammonemia even in the presence of normal liver function tests. This hyperammonemic state can lead to encephalopathy referred as Valproate induced hyperammonemic encephalopathy (VHE). Here we present a case of valproate induced hyperammonemic encephalopathy in a young male caused by initiation of valproate therapy.
丙戊酸盐是一种常用的抗惊厥药物。即使肝功能检查正常，它也有导致高氨血症的可能性。这种高氨血症状态可导致被称为丙戊酸盐诱导的高氨血症性脑病（VHE）的脑病。在此，我们报告一例因开始使用丙戊酸盐治疗而导致的年轻男性丙戊酸盐诱导的高氨血症性脑病病例。
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