Saust Laura Trolle, Siersma Volkert, Lykkegaard Jesper, Bjerrum Lars, Hansen Malene Plejdrup
Center for General Practice, Department of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark.
Section of General Practice and Research Unit for General Practice, Department of Public Health, University of Copenhagen, 1353 Copenhagen, Denmark.
Antibiotics (Basel). 2022 Dec 5;11(12):1759. doi: 10.3390/antibiotics11121759.
Rational antibiotic treatment of urinary tract infections (UTI) is important. To improve the quality of antibiotic treatment of UTI, it is essential to obtain insight into diagnostic approaches and prescribing patterns in general practice. The aim of this study was to investigate the quality of diagnostics and treatment of UTI in general practice by means of quality indicators (QIs). QIs provide a quantitative measure of quality and are defined by a numerator (the number of patients receiving a specific investigation or treatment) and a denominator (the number of patients included in the quality assessment). For adult patients with suspected UTI, practices registered the following: age, sex, risk factors, symptoms and signs, examinations, diagnosis and treatment. The levels of the QIs were compared with their corresponding standards. Half of the patients diagnosed with lower UTI or pyelonephritis fulfilled the diagnostic criteria for UTI: characteristic UTI symptoms and clear signs of bacteriuria, respectively. Urinalysis was performed for nearly all patients, including patients without characteristic symptoms of UTI. One-fourth of the patients with suspected lower UTI were treated with antibiotics despite no urinalysis and nearly half received antibiotics despite an inconclusive dipstick test. Pivmecillam was the preferred antibiotic. The findings of this study indicate that there is room for improvement in the management of UTI in Danish general practice.
合理使用抗生素治疗尿路感染(UTI)至关重要。为提高UTI抗生素治疗质量,深入了解全科医疗中的诊断方法和处方模式必不可少。本研究旨在通过质量指标(QIs)调查全科医疗中UTI的诊断和治疗质量。QIs提供了一种质量的定量衡量方法,由分子(接受特定检查或治疗的患者数量)和分母(纳入质量评估的患者数量)定义。对于疑似UTI的成年患者,医疗机构记录了以下信息:年龄、性别、危险因素、症状和体征、检查、诊断和治疗。将QIs水平与其相应标准进行了比较。被诊断为下尿路感染或肾盂肾炎的患者中,分别有一半符合UTI的诊断标准:分别为典型的UTI症状和明确的菌尿迹象。几乎对所有患者都进行了尿液分析,包括没有UTI典型症状的患者。四分之一疑似下尿路感染的患者在未进行尿液分析的情况下接受了抗生素治疗,近一半患者尽管试纸检测结果不确定仍接受了抗生素治疗。匹美西林是首选抗生素。本研究结果表明,丹麦全科医疗中UTI的管理仍有改进空间。