Moniod Louise, Hovine Agathe, Trombert Béatrice, Rancon Florence, Zufferey Paul, Chauveau Laura, Chauleur Céline, Raia-Barjat Tiphaine
Department of Gynaecology and Obstetrics, University Hospital of Saint-Etienne, 42000 Saint-Etienne, France.
Department of Public Health, University Hospital of Saint-Etienne, 42000 Saint Etienne, France.
Healthcare (Basel). 2022 Dec 18;10(12):2569. doi: 10.3390/healthcare10122569.
In prolonged pregnancies, the risks of neonatal morbidity and mortality are increased. The aim of this trial was to assess the benefits of maternal information about fetal movement (FM) counting on neonatal outcomes in prolonged pregnancy. It was a prospective, single center, randomized, open-label study conducted from October 2019 to March 2022. Intention-to-treat analyses were performed on 278 patients randomized into two 1:1 groups (control group and FM counting group). The primary outcome was a composite score of neonatal morbidity (presence of two of the following items: fetal heart rate abnormality at delivery, Apgar score of <7 at 5 min, umbilical cord arterial pH of <7.20, and acute respiratory distress with mutation in neonatal intensive care unit). There was no significant difference between the two groups in the rate of neonatal morbidity (14.0% in the FM counting group versus 22.9% in the standard information group; p = 0.063; OR 0.55, 95% CI 0.29−1.0). In this study, fetal movement counting for women in prolonged pregnancy failed to demonstrate a significant reduction in adverse neonatal outcomes.
在过期妊娠中，新生儿发病和死亡的风险会增加。本试验的目的是评估向母亲提供胎动（FM）计数信息对过期妊娠新生儿结局的益处。这是一项前瞻性、单中心、随机、开放标签研究，于2019年10月至2022年3月进行。对随机分为两个1:1组（对照组和FM计数组）的278例患者进行了意向性分析。主要结局是新生儿发病的综合评分（存在以下两项：分娩时胎儿心率异常、5分钟时阿氏评分<7、脐动脉pH值<7.20以及新生儿重症监护病房出现急性呼吸窘迫伴病情突变）。两组新生儿发病率无显著差异（FM计数组为14.0%，标准信息组为22.9%；p = 0.063；OR 0.55，95%CI 0.29−1.0）。在本研究中，对过期妊娠妇女进行胎动计数未能显著降低不良新生儿结局。
Zotero 插件