了解多发性硬化症对整体心理健康及各维度的影响。
Understanding the Effect of Multiple Sclerosis on General and Dimensions of Mental Health.
作者信息
Kang Weixi
机构信息
UK DRI Care Research and Technology Centre, Department of Brain Sciences, Imperial College London, 926, Sir Michael Uren Hub, 86 Wood Lane, London W12 0BZ, UK.
出版信息
J Clin Med. 2022 Dec 16;11(24):7483. doi: 10.3390/jcm11247483.
OBJECTIVE
The objective of the current study is to investigate how general and dimensions of mental health are affected by multiple sclerosis (MS).
METHODS
Factor analysis, generalized linear models, and one-sample t-tests were used to analyze data from 78 people with MS with a mean age of 52.19 (S.D. = 12.94) years old and 25.64% males and 38,516 people without MS with a mean age of 49.10 (S.D. = 18.24) years old and 44.27% males from Understanding Society.
RESULTS
The current study found that there are three underlying factors of the GHQ-12 labeled as GHQ-12A (social dysfunction and anhedonia; 6 items), GHQ-12B (depression and anxiety; 4 items), and GHQ-12C (loss of confidence; 2 items), and the general mental health, GHQ-12A (social dysfunction and anhedonia), and GHQ-12C (loss of confidence) are associated with MS.
CONCLUSIONS
Effective mental health management in MS patients is important given mental health in people with MS is linked to the onset of MS and exacerbating disease progression/relapses.
目的
本研究的目的是调查多发性硬化症（MS）如何影响心理健康的总体状况及其维度。
方法
采用因子分析、广义线性模型和单样本t检验，对来自“理解社会”项目的78名平均年龄为52.19岁（标准差=12.94）、男性占25.64%的MS患者以及38516名平均年龄为49.10岁（标准差=18.24）、男性占44.27%的非MS患者的数据进行分析。
结果
本研究发现，一般健康问卷12项（GHQ-12）有三个潜在因子，分别标记为GHQ-12A（社会功能障碍和快感缺乏；6项）、GHQ-12B（抑郁和焦虑；4项）和GHQ-12C（信心丧失；2项），且总体心理健康、GHQ-12A（社会功能障碍和快感缺乏）以及GHQ-12C（信心丧失）与MS相关。
结论
鉴于MS患者的心理健康与MS的发病以及疾病进展/复发的加剧有关，对MS患者进行有效的心理健康管理很重要。
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