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关节炎患者心理健康的全球范围及维度

Global and Dimensions of Mental Health in Arthritis Patients.

作者信息

Kang Weixi

机构信息

Department of Brain Sciences, Imperial College, London W12 0BZ, UK.

出版信息

Healthcare (Basel). 2023 Jan 9;11(2):195. doi: 10.3390/healthcare11020195.

DOI:10.3390/healthcare11020195
PMID:36673563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9859167/
Abstract

Arthritis is one of the main clusters of long-lasting musculoskeletal and joint disorders. Recently, there has been increasing interest in the impact of arthritis patients' mental health, which has mainly focused on depression and anxiety in clinical samples. However, much less is known about how domains of mental health based on the widely used 12-item version of the general health survey (GHQ-12) are affected by arthritis. The current research answered this question using confirmatory factor analysis, general linear models, and one-sample t-tests on a nationally representative sample from the United Kingdom with 5588 arthritis patients and 8794 participants indicating that they were not clinically diagnosed with arthritis. The current study found that (1) a total of three factors of GHQ-12 that are labeled GHQ-12A (social dysfunction and anhedonia; six items), GHQ-12B (depression and anxiety; four items), and GHQ-12C (loss of confidence; two items), and (2) both the global mental health and dimensions of mental health are negatively affected by arthritis. Clinicians could use the results from the present study to make better treatment decisions for patients with arthritis.

摘要

关节炎是长期存在的肌肉骨骼和关节疾病的主要类型之一。最近,人们对关节炎患者心理健康的影响越来越感兴趣,这主要集中在临床样本中的抑郁和焦虑方面。然而,对于基于广泛使用的12项一般健康调查问卷(GHQ - 12)的心理健康领域如何受到关节炎影响,我们所知甚少。当前的研究通过对来自英国的具有全国代表性的样本进行验证性因素分析、一般线性模型和单样本t检验,回答了这个问题,该样本中有5588名关节炎患者和8794名表示未被临床诊断为关节炎的参与者。当前的研究发现:(1)GHQ - 12共有三个因素,分别标记为GHQ - 12A(社交功能障碍和快感缺乏;六项)、GHQ - 12B(抑郁和焦虑;四项)和GHQ - 12C(信心丧失;两项);(2)整体心理健康和心理健康维度均受到关节炎的负面影响。临床医生可以利用本研究的结果为关节炎患者做出更好的治疗决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28b7/9859167/3da7c3956e48/healthcare-11-00195-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28b7/9859167/3da7c3956e48/healthcare-11-00195-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28b7/9859167/3da7c3956e48/healthcare-11-00195-g001.jpg

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本文引用的文献

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Rheumatol Ther. 2020 Sep;7(3):457-471. doi: 10.1007/s40744-020-00217-4. Epub 2020 Jun 13.
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Understanding the population structure of the GHQ-12: Methodological considerations in dimensionally complex measurement outcomes.了解 GHQ-12 的人口结构:维度复杂测量结果中的方法学考虑。
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Systematic review of mental health comorbidities in psoriatic arthritis.
中国社区中老年人群关节炎风险预测模型的开发与验证
Heliyon. 2024 Jan 16;10(2):e24526. doi: 10.1016/j.heliyon.2024.e24526. eCollection 2024 Jan 30.
系统性综述银屑病关节炎的精神共病。
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Fatigue, Sleep, and Autoimmune and Related Disorders.疲劳、睡眠与自身免疫及相关紊乱。
Front Immunol. 2019 Aug 6;10:1827. doi: 10.3389/fimmu.2019.01827. eCollection 2019.
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The factor structure of the general health questionnaire (GHQ12) in Saudi Arabia.沙特阿拉伯一般健康问卷(GHQ12)的因子结构。
BMC Health Serv Res. 2018 Aug 2;18(1):595. doi: 10.1186/s12913-018-3381-6.
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Concomitant fibromyalgia complicating chronic inflammatory arthritis: a systematic review and meta-analysis.同时患有纤维肌痛症和慢性炎症性关节炎:系统评价和荟萃分析。
Rheumatology (Oxford). 2018 Aug 1;57(8):1453-1460. doi: 10.1093/rheumatology/key112.
7
TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis.胶原诱导关节炎小鼠模型中 TNFα 依赖性快感缺失和海马血清素转运体活性上调。
Neuropharmacology. 2018 Jul 15;137:211-220. doi: 10.1016/j.neuropharm.2018.04.023. Epub 2018 May 1.
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Brain-derived neurotrophic factor in adjuvant-induced arthritis in rats. Relationship with inflammation and endothelial dysfunction.脑源性神经营养因子在大鼠佐剂性关节炎中的作用。与炎症和内皮功能障碍的关系。
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The psychometric properties of GHQ for detecting common mental disorder among community dwelling men in Goa, India.在印度果阿邦社区居住男性中,用于检测常见精神障碍的一般健康问卷(GHQ)的心理测量特性。
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