Kang Weixi, Whelan Edward, Pineda Hernández Sònia
UK DRI Care Research and Technology Centre, Department of Brain Sciences, Imperial College London, London W12 0BZ, UK.
Independent Researcher, 99MX QH Maynooth, Ireland.
Healthcare (Basel). 2023 Jul 12;11(14):2009. doi: 10.3390/healthcare11142009.
Although previous studies have investigated the presence of psychometric comorbidities in individuals with emphysema, our understanding of the impact of emphysema on general mental health and specific dimensions of mental health, such as social dysfunction and anhedonia, depression and anxiety, and loss of confidence, remains limited. This research aims to examine the influence of emphysema on general mental health and its dimensions using the GHQ-12 assessment. By employing confirmatory factor analysis (CFA), the predictive normative approach, and one-sample -test, we analyzed data from Understanding Society: the UK Household Longitudinal Study (UKHLS), including 97 individuals clinically diagnosed with emphysema and 8980 individuals without a clinical diagnosis of emphysema. The findings of this study indicate that individuals with clinically diagnosed emphysema experience poorer general mental health (t(96) = 8.41, < 0.001, Cohen's d = 0.12, 95% C.I. [0.09, 0.15]), increased levels of social dysfunction and anhedonia (t(96) = 6.02, < 0.001, Cohen's d = 0.09, 95% C.I. [0.06, 0.11]), heightened depression and anxiety (t(96) = 7.26, < 0.001, Cohen's d = 0.11, 95% C.I. [0.08, 0.14]), as well as elevated loss of confidence (t(96) = 6.40, < 0.001, Cohen's d = 0.09, 95% C.I. [0.07, 0.12]). These findings suggest the need for intervention programs aimed at improving the mental health of individuals with emphysema.
尽管先前的研究已经调查了肺气肿患者中存在的心理测量共病情况，但我们对肺气肿对总体心理健康以及心理健康的特定维度（如社会功能障碍和快感缺失、抑郁和焦虑以及信心丧失）的影响的理解仍然有限。本研究旨在使用一般健康问卷12项（GHQ - 12）评估来检验肺气肿对总体心理健康及其维度的影响。通过采用验证性因素分析（CFA）、预测规范方法和单样本t检验，我们分析了来自“理解社会”：英国家庭纵向研究（UKHLS）的数据，其中包括97名临床诊断为肺气肿的个体和8980名无肺气肿临床诊断的个体。本研究结果表明，临床诊断为肺气肿的个体总体心理健康状况较差（t(96)=8.41，p<0.001，科恩d值 = 0.12，95%置信区间[0.09, 0.15]），社会功能障碍和快感缺失水平升高（t(96)=6.02，p<0.001，科恩d值 = 0.09，95%置信区间[0.06, 0.11]），抑郁和焦虑加剧（t(96)=7.26，p<0.001，科恩d值 = 0.11，95%置信区间[0.08, 0.14]），以及信心丧失加剧（t(96)=6.40，p<0.001，科恩d值 = 0.09，95%置信区间[0.07, 0.12]）。这些发现表明需要制定旨在改善肺气肿患者心理健康的干预计划。
